Dietary polyphenols as modulators of lipid oxidation and mitochondrial function in overweight volunteers - Polyphenols and fat oxidation

niversiteit Maastricht0 个研究点目标入组 60 人开始时间: 待定最近更新: 2024年5月6日

适应症

试验速览

暂无简介。

•- Overweight men and women (BMI>=25kg/m2- 34.9kg/m2),
•- Aged 20-35 and 35-50 years
•- Caucasian
•- Normal fasting glucose (< 6.1 mmol/L)
•- Normal blood pressure (systolic blood pressure 100-140 mmHg, diastolic blood pressure 60-90 mmHg)
•- Weight stable in last 3 months (± 2kg).

•- Women lactating, pregnant or (post) menopausal
•- Regular smokers
•- People with intensive fitness training, eg. athletes (>= 3 per week >= 1 hour training)
•- Habitual consumption of green tea (more than 1 cup per day) or products containing green tea extract
•- Total caffeine consumption > 300 mg/day (1 can of cola or 2 cups of regular coffee or 2 cups of black tea or 1 cup of coffee and 1 cup of black tea or other combinations)
•- Alcohol intake >20 g/day (2 glasses of beer or wine)
•- Any dietary vitamins or dietary supplements
•- Diabetes mellitus (defined as FPG >= 7.0 mmol/l and/or 2hPG >= 11.1 mmol/l)
•- Serious pulmonary, cardiovascular, hepatic or renal disease
•- History of cardiovascular disease
•- All other relevant medical disorders that potentially interfere with this trial (e.g. history of gastro-intestinal, liver or thyroid disorders)
•- Current use of medication interfering with study intervention or interfering with study endpoints/hypotheses (e.g. medication containing caffeine like analgesics, anorectics and analeptics)
•- Not to be able to understand the study information
•- Subjects on a special diet or vegetarian
•- Blood donation 2 months prior to the study and during the study
•- Participation in other studies
•- Drug use
•- Use of anti-coagulant medication

发起方