Influence of Timing on Motor Learning
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 17
- 试验地点
- 2
- 主要终点
- Box and Block Test
研究概览
简要总结
The investigators are trying to determine the therapeutic effect of the music glove and conventional hand exercise program to the subacute stroke patients. All participants will be randomized into two groups: AB and BA. They will all exercise at least 3 times a week for 3 weeks with a minimal 3 hours exercise time per week. Participants will receive the other intervention at 3-month post stroke date. Clinical evaluations will be performed at baseline, post therapy after first intervention, 3-week post intervention follow up, 3-month post stroke, post therapy after second intervention, 3-week post second intervention follow up, and 6-month post stroke follow up visits.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Treatment
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •History of a single stroke at least 1 week prior to enrollment
- •Upper Extremity weakness measured on a standard clinical scale
- •No active major psychiatric problems, or neurological/orthopedic problems affecting the stroke affected upper extremity
- •No active major neurological disease other than the stroke
- •Absence of pain in the affected upper extremity
排除标准
- •Severe tone at the affected upper extremity as measured on a standard clinical scale
- •Severe aphasia as measured on a standard clinical scale
- •Severe reduced level of consciousness
- •Severe sensory/proprioception deficit at the affected upper extremity as measured on a standard clinical scale
- •Currently pregnant
- •Difficulty in understanding or complying with instructions given by the experimenter
- •Inability to perform the experimental task that will be studied
- •Increased pain with movement of the affected upper extremity
结局指标
主要结局
Box and Block Test
时间窗: From baseline to end of therapy (3 weeks)
We compared the change of Box and Block Test scores from baseline evaluation to the end of 3-week of therapy (Intervention 1), and from 12-week post-stroke to end of 3-week therapy (Intervention 2). Participants are instructed to move as many blocks as possible, one at a time, from one compartment in a box to a second compartment over a divider for a period of 60 seconds; each block that is moved is counted, and multiple blocks moved at the same time are counted as a single block. The higher scores indicates a better outcome.
次要结局
- Fugl-Meyer Motor Assessment of the Upper Extremity(From baseline to end of therapy (3 weeks))
- Action Research Arm Test(From baseline to end of therapy (3 weeks))
- 9-Hole Peg Test(From baseline to end of therapy (3 week))
研究者
David Reinkensmeyer
Assistant Professor, Department of Neurology
University of California, Irvine