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Clinical Trials/NCT02410629
NCT02410629
Completed
Not Applicable

Influence of Timing on Motor Learning

David Reinkensmeyer1 site in 1 country17 target enrollmentMarch 2015

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Cerebrovascular Accident
Sponsor
David Reinkensmeyer
Enrollment
17
Locations
1
Primary Endpoint
Box and Block Test
Status
Completed
Last Updated
3 years ago

Overview

Brief Summary

The investigators are trying to determine the therapeutic effect of the music glove and conventional hand exercise program to the subacute stroke patients. All participants will be randomized into two groups: AB and BA. They will all exercise at least 3 times a week for 3 weeks with a minimal 3 hours exercise time per week. Participants will receive the other intervention at 3-month post stroke date. Clinical evaluations will be performed at baseline, post therapy after first intervention, 3-week post intervention follow up, 3-month post stroke, post therapy after second intervention, 3-week post second intervention follow up, and 6-month post stroke follow up visits.

Registry
clinicaltrials.gov
Start Date
March 2015
End Date
July 2016
Last Updated
3 years ago
Study Type
Interventional
Study Design
Crossover
Sex
All

Investigators

Sponsor
David Reinkensmeyer
Responsible Party
Sponsor Investigator
Principal Investigator

David Reinkensmeyer

Assistant Professor, Department of Neurology

University of California, Irvine

Eligibility Criteria

Inclusion Criteria

  • History of a single stroke at least 1 week prior to enrollment
  • Upper Extremity weakness measured on a standard clinical scale
  • No active major psychiatric problems, or neurological/orthopedic problems affecting the stroke affected upper extremity
  • No active major neurological disease other than the stroke
  • Absence of pain in the affected upper extremity

Exclusion Criteria

  • Severe tone at the affected upper extremity as measured on a standard clinical scale
  • Severe aphasia as measured on a standard clinical scale
  • Severe reduced level of consciousness
  • Severe sensory/proprioception deficit at the affected upper extremity as measured on a standard clinical scale
  • Currently pregnant
  • Difficulty in understanding or complying with instructions given by the experimenter
  • Inability to perform the experimental task that will be studied
  • Increased pain with movement of the affected upper extremity

Outcomes

Primary Outcomes

Box and Block Test

Time Frame: From baseline to end of therapy (3 weeks)

We compared the change of Box and Block Test scores from baseline evaluation to the end of 3-week of therapy (Intervention 1), and from 12-week post-stroke to end of 3-week therapy (Intervention 2). Participants are instructed to move as many blocks as possible, one at a time, from one compartment in a box to a second compartment over a divider for a period of 60 seconds; each block that is moved is counted, and multiple blocks moved at the same time are counted as a single block. The higher scores indicates a better outcome.

Secondary Outcomes

  • Fugl-Meyer Motor Assessment of the Upper Extremity(From baseline to end of therapy (3 weeks))
  • Action Research Arm Test(From baseline to end of therapy (3 weeks))
  • 9-Hole Peg Test(From baseline to end of therapy (3 week))

Study Sites (1)

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