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Clinical Trials/NCT02048826
NCT02048826
Completed
Not Applicable

Study of Influence of Timing on Motor Learning

University of California, Irvine1 site in 1 country31 target enrollmentNovember 2013

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Cerebrovascular Accident
Sponsor
University of California, Irvine
Enrollment
31
Locations
1
Primary Endpoint
Motor and Strength Outcome Measure Using Box and Block Test Measured in Units of Blocks Placed
Status
Completed
Last Updated
5 years ago

Overview

Brief Summary

The purpose of this study is to determine the effectiveness of training hand movement using FINGER robot after stroke. FINGER is a robot that measures finger movements and allows users to play computer games using those movements.

Detailed Description

Robotic devices can be used to retrain movement after stroke. However, it is unclear how best to assist in movement. Providing physical assistance may improve the flow of proprioceptive information to the nervous system, which may help a person relearn to move a limb. On the other hand, assisting movement with a robot may cause a person to "slack", not trying as hard during therapy. This study will test the effect of different levels of assistance on recovery of finger function during robot-assisted therapy after stroke.

Registry
clinicaltrials.gov
Start Date
November 2013
End Date
February 2016
Last Updated
5 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

David Reinkensmeyer

Professor of Anatomy and Neurobiology

University of California, Irvine

Eligibility Criteria

Inclusion Criteria

  • Age 18 to 80 years of age
  • Have history of stroke affecting the arm, at least 6 months prior to enrollment
  • have arm and/or hand weakness as measured on a standard clinical scale
  • do not have active major psychological problems, or problems affecting the stroke-affected arm or hand besides the stroke
  • do not have active major brain disease other than the stroke
  • have absence of pain in the stroke-affected arm and hand

Exclusion Criteria

  • severe stiffness of the arm or hand as measured on a standard clinical scale
  • severe problems speaking or understanding speech as measured on a standard clinical scale
  • severe reduced level of consciousness
  • severe loss ability to sense movement of your limbs as measured on a standard clinical scale
  • currently pregnant
  • difficulty in understanding or complying with the instructions given by the researcher
  • inability to perform the experimental task that will be studied
  • increased pain with movement of the stroke-affected arm or hand
  • Exclusion criteria that will prevent subjects from participating in the MRI:
  • Subjects having any implanted metal such as metallic splinters, metallic surgical clips, prosthetic heart valves, pacemakers, neuro-stimulation devices, orthodontic work that contains ferromagnetic materials,

Outcomes

Primary Outcomes

Motor and Strength Outcome Measure Using Box and Block Test Measured in Units of Blocks Placed

Time Frame: From baseline to 1-month post therapy

The primary endpoint was the change in Box and Blocks score, which measures how many blocks a subject can pick up and place in a box in 60 seconds, from baseline to 1-month post-therapy. The higher the scores, the better arm and hand function indicated.

Secondary Outcomes

  • Motor and Strength Measure Using Action Research Arm Test Measured as a Score(From baseline to 1-month post therapy)
  • Motor, Strength and Sensory Using Fugl-Meyer Test Measured as a Score(From baseline to 1-month post therapy)

Study Sites (1)

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