Effects of Iranian Propolis supplementation on kidney functio
Phase 3
- Conditions
- Condition 1: Chronic kidney disease (CKD), stage 2. Condition 2: Chronic kidney disease (CKD), stage 3.Chronic kidney disease, stage 2 (mild)Chronic kidney disease, stage 3 (moderate)N18.2N18.3
- Registration Number
- IRCT20191214045727N1
- Lead Sponsor
- Tabriz University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 44
Inclusion Criteria
The tendency to participate in the study
Having stage 2 or 3 CKD according to eGFR of 30-89 ml/min per 1.73 m2
Age: 20-80 years old
Exclusion Criteria
BMI less than 18.5 or more than 35 kg/m2
Having replaced kidney
Pregnancy or breastfeeding
Having any kind of allergy or asthma
Receiving steroids or other immune system suppressors
Taking herbals in last 3 months
Smoking, Being addicted, consuming alcohol or opioids
Doing professional sports
Having chronic inflammatory disease (rheumatoid arthritis, IBD), severe depression, schizophrenia, sever liver failure, liver cirrhosis, cancers, severe infection
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Kidney function (albuminuria, urea, and creatinine clearance). Timepoint: At the beginning and end of the study. Method of measurement: Biochemical method.;Inflammation status. Timepoint: At the beginning and end of the study. Method of measurement: Immunoassay method.;Lipid profile. Timepoint: At the beginning and end of the study. Method of measurement: Biochemical method.
- Secondary Outcome Measures
Name Time Method utritional status. Timepoint: At the beginning of the study, and every month until the end of the study. Method of measurement: The appetite, food recall and 3-day food record questionnaires.