Effects of sugammadex on the incidence of postoperative nausea and vomiting in patients undergoing laparoscopic abdominal surgery
- Conditions
- Symptoms, signs and abnormal clinical and laboratory findings, NEC
- Registration Number
- KCT0008895
- Lead Sponsor
- Seoul National University Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot yet recruiting
- Sex
- All
- Target Recruitment
- 136
Patients who are (1) adults aged 20 or older undergoing laparoscopic abdominal surgery through regular procedures at the hospital, (2) adult patients using intravenous patient-controlled analgesia (PCA) after surgery, and (3) able to provide written informed consent to participate in the clinical trial and understand the procedures of this clinical trial.
(1) Smokers
(2) Patients with severe bradycardia and uncontrollable arrhythmias
(3) Patients who received both sugammadex and neostigmine for neuromuscular blockade reversal at the end of general anesthesia
(4) Patients who underwent postoperative mechanical ventilation
(5) Patients who underwent reoperation within 48 hours after surgery
(6) For patients who underwent reoperation more than 48 hours after the initial surgery, only the first surgery will be included in the study, and subsequent surgeries will be excluded.
(7) Patients discharged on the same day as surgery
(8) Patients who used neuromuscular blocking agents other than rocuronium during anesthesia induction
Study & Design
- Study Type
- Interventional Study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Occurrence of PONV (Postoperative Nausea and Vomiting) within 2 days after surgery
- Secondary Outcome Measures
Name Time Method Occurrence of PONV (Postoperative Nausea and Vomiting) in the recovery room;The type and total dosage of antiemetics administered up to the second day after surgery;The usage of IV-PCA (Intravenous Patient-Controlled Analgesia) up to 24 hours after surgery;The type and quantity of analgesics used post-surgery;The NRS (Numerical Rating Scale) for surgical site pain up to the second day after surgery;Occurrence of complications rated III or higher according to the Clavien-Dindo classification;Length of hospital stay