Removal of Uremic Toxins With Nocturnal Dialysis Versus Standard Dialysis

Not Applicable

Completed

• Conditions: Chronic Renal Failure
• Interventions: Procedure: Nocturnal dialysis; Procedure: Standard dialysis

• Registration Number: NCT00766792
• Lead Sponsor: University Hospital, Ghent

Brief Summary

Dialysis patients, who decide to switch from standard dialysis (3 times 240-270 min/week) to nocturnal dialysis (3 times 480 min/week), will be followed. In parallel a control group with patients staying on standard dialysis will be followed. The study will last 30 weeks. During this period blood samples (pre- and post-dialysis: 10 times; inlet and outlet of dialyzer: 3 times) will be collected on predetermined time points. Concentration of several uremic retention solutes will be determined.

Detailed Description

Not available

Study Timeline

• Study Start: 2005-12
• Primary Completion: 2008-07
• Study Completion: 2008-07
• Status Verified: 2008-10
• Study First Submitted: 2008-10-03
• Study First Submitted QC: 2008-10-03
• Study First Posted: 2008-10-06
• Last Update Submitted: 2008-10-30
• Last Update Posted: 2008-10-31

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 15

Inclusion Criteria

• age > 18 years

Exclusion Criteria

• pregnancy

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
1	Nocturnal dialysis	Nocturnal dialysis
2	Standard dialysis	Standard dialysis

Primary Outcome Measures

Name	Time	Method
To evaluate what is more effective for removal of uremic toxins - nocturnal versus standard dialysis?	30 weeks

Trial Locations

Locations (1)

University Hospital Ghent; 🇧🇪 Ghent, Belgium