Study of Clinical Outcomes of More Frequent Hemodialysis
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 46
- 试验地点
- 4
- 主要终点
- Hospitalization days per year
研究概览
简要总结
The study compares the benefits of short daily hemodialysis six days a week, nocturnal (night time) hemodialysis six days a week, every other day and every other night hemodialysis to traditional three days a week hemodialysis.The hypothesis is that increasing hemodialysis treatment time and/or frequency will improve outcomes.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Stable vascular access, i.e., lack of needling difficulties and stable flow rates. Accesses will include fistulae, grafts, catheters and ports.
- •18 years of age.
- •History of compliance with a dialysis treatment schedule, or if a new patient, express a willingness to be compliant with a treatment schedule.
- •Plan to continue care and follow-up at the investigational site.
- •Able to sign the informed consent and other relevant documents.
排除标准
- •History of poor compliance with thrice (or twice) weekly dialysis schedules as manifested by more than three unexplained missed treatments in the past six (6) months.
- •Pregnancy.
- •Intravenous drug abuser.
- •Expects to receive a transplant or transfer to another facility within six months of entering the study.
研究组 & 干预措施
A
Six Day per week short daily hemodialysis
干预措施: More frequent hemodialysis (Procedure)
B
Six nights per week nocturnal hemodialysis
干预措施: More frequent hemodialysis (Procedure)
E
5 days per week short daily hemodialysis
干预措施: More frequent hemodialysis (Procedure)
F
5 nights per week hemodialysis
干预措施: More frequent hemodialysis (Procedure)
G
Conventional three time per week short daily hemodialysis
干预措施: Conventional Hemodialysis (Procedure)
C
Every other day short daily hemodialysis
干预措施: More frequent hemodialysis (Procedure)
D
Every other night hemodialysis
干预措施: More frequent hemodialysis (Procedure)
结局指标
主要结局
Hospitalization days per year
时间窗: Ongoing
次要结局
- Nutritional Status measured by Subjective Global Assessment(Ongoing)
- Control of hypertension, as measured by number of antihypertensive tablets taken per day(Ongoing)
- Control of hyperphosphatemia, as measured by number of phosphate binder tablets taken per day(Ongoing)
- Anemia, measured by erythropoetin dose(Ongoing)