More Frequent Dialysis (>3 Treatments Per Week)

Not Applicable

Completed

• Conditions: Chronic Kidney Disease; End Stage Renal Disease
• Interventions: Procedure: More frequent hemodialysis; Procedure: Conventional Hemodialysis

• Registration Number: NCT00575497
• Lead Sponsor: Satellite Healthcare

Brief Summary

The study compares the benefits of short daily hemodialysis six days a week, nocturnal (night time) hemodialysis six days a week, every other day and every other night hemodialysis to traditional three days a week hemodialysis.The hypothesis is that increasing hemodialysis treatment time and/or frequency will improve outcomes.

Detailed Description

Not available

Study Timeline

• Study Start: 2005-01
• Study First Submitted: 2007-12-14
• Study First Submitted QC: 2007-12-17
• Study First Posted: 2007-12-18
• Primary Completion: 2012-08-07
• Study Completion: 2012-08-07
• Status Verified: 2019-04
• Last Update Submitted: 2019-04-17
• Last Update Posted: 2019-04-19

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 46

Inclusion Criteria

• Stable vascular access, i.e., lack of needling difficulties and stable flow rates. Accesses will include fistulae, grafts, catheters and ports.
• 18 years of age.
• History of compliance with a dialysis treatment schedule, or if a new patient, express a willingness to be compliant with a treatment schedule.
• Plan to continue care and follow-up at the investigational site.
• Able to sign the informed consent and other relevant documents.

Exclusion Criteria

• History of poor compliance with thrice (or twice) weekly dialysis schedules as manifested by more than three unexplained missed treatments in the past six (6) months.
• Pregnancy.
• Intravenous drug abuser.
• Expects to receive a transplant or transfer to another facility within six months of entering the study.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
D	More frequent hemodialysis	Every other night hemodialysis
F	More frequent hemodialysis	5 nights per week hemodialysis
A	More frequent hemodialysis	Six Day per week short daily hemodialysis
G	Conventional Hemodialysis	Conventional three time per week short daily hemodialysis
B	More frequent hemodialysis	Six nights per week nocturnal hemodialysis
C	More frequent hemodialysis	Every other day short daily hemodialysis
E	More frequent hemodialysis	5 days per week short daily hemodialysis

Primary Outcome Measures

Name	Time	Method
Hospitalization days per year	Ongoing

Secondary Outcome Measures

Name	Time	Method
Nutritional Status measured by Subjective Global Assessment	Ongoing
Control of hypertension, as measured by number of antihypertensive tablets taken per day	Ongoing
Control of hyperphosphatemia, as measured by number of phosphate binder tablets taken per day	Ongoing
Anemia, measured by erythropoetin dose	Ongoing

Trial Locations

Locations (2)

Satellite Healthcare, Inc.; 🇺🇸 Mountain View, California, United States

WellBound, Inc.; 🇺🇸 Mountain View, California, United States