Evaluation of a rehabilitation group intervention in patients with persistent depressive disorder and their partner.
Not yet recruiting
- Conditions
- Persistent Depressive DisorderTherapie-Resistente Depressie.Chronic Depressive DisorderTreatment-Resistent Depression.Persisterende Depressieve StoornisChronisch Depressieve Stoornis
- Registration Number
- NL-OMON20302
- Lead Sponsor
- eiden University Medical Centre (LUMC), Department of Psychiatry
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Not specified
- Target Recruitment
- 514
Inclusion Criteria
Patients > 18 years with primary diagnosis Persistent Depressive Disorder.
Exclusion Criteria
Severe psychiatric (co)morbidity (e.g. substance abuse, suicidality, psychotic) and/or severe somatic comorbidty; cognitive problems; insufficient Dutch language proficiency.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Quality of life (QALYs).
- Secondary Outcome Measures
Name Time Method Costs, psychopathology, resilience, disease burden.
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms underlie persistent depressive disorder and how might PPEP4All intervention address them?
How does the PPEP4All group intervention compare to standard antidepressant therapies in treatment-resistant depression?
Are there specific biomarkers that can predict response to psychiatric rehabilitation programs like PPEP4All in chronic depression?
What are the potential adverse events associated with PPEP4All and how do they compare to usual care for persistent depressive disorder?
How does the LUMC-led PPEP4All program integrate with existing pharmacological treatments for depression and what are the outcomes?