Vitamin D Status in Children With Sickle Cell Disease Living in Lyon, France
Completed
- Conditions
- Vitamin D DeficiencySickle Cell Disease
- Registration Number
- NCT04694976
- Lead Sponsor
- Hospices Civils de Lyon
- Brief Summary
Vitamin D deficiency may be under-diagnosed in sickle cell disease French children. Therefore, the investigator need an epidemiologic study about the prevalence of vitamin D deficiency in this specific population. There are not specific guidelines neither testing nor treatment. The investigator propose to test vitamin D status in all children with sickle cell disease who are consulting their referring haematologist doctor or in the emergency ward.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 130
Inclusion Criteria
- Children: under 18 years old
- Sickle cell any genetic type homozygous or composite heterozygous
- To receive an assessment independently of the study, during a presentation to the emergency ward and/or a follow-up consultation by the hematologist
- no parental opposition signed by at least one parent/legal representative and no child opposition
- social security beneficiary
Exclusion Criteria
- History of hematologic grafting
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Determination of 25-OH Vitamin D level Day 1 We classify vitamin D status as follows :
* Sufficiency \> \>75nmol/L (\>30 ng/mL)
* Insufficiency 50-75 nmol/L (20-30 ng/mL)
* Deficiency 12-50nmol/L (5-20 ng/mL)
* Severe deficiency \<12 nmol/L (\<5 ng/mL)
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Hôpital Femme Mère enfant - Urgences pédiatriques
🇫🇷Bron, France
Hôpital Femme Mère enfant - Urgences pédiatriques🇫🇷Bron, France