Macroscopic and Molecular Changes in Knee Muscular-tendon Unit in Response to Acute Resistant Load
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Quadriceps Muscle
- Sponsor
- Hillel Yaffe Medical Center
- Enrollment
- 300
- Locations
- 1
- Primary Endpoint
- Ultrasound Changes in Knee Muscle and Tendon
- Last Updated
- 6 years ago
Overview
Brief Summary
The aim of this study is to determine the influence of acute resistance exercises on anatomical and biological changes in the quadriceps muscle and tendons of the knee
Investigators
Eligibility Criteria
Inclusion Criteria
- •Non-professional athletes
- •Pass heart/lung endurance tests
- •Pass ergometrics testing
Exclusion Criteria
- •Have been injured
- •Had physiotherapy for back or lower limbs in past 6 months
- •Orthopedic surgery in lower limbs
Outcomes
Primary Outcomes
Ultrasound Changes in Knee Muscle and Tendon
Time Frame: One year
Comparison of results of pre- and post ultrasound changes after interventions between the 3 groups
Biopsy Changes in Knee Muscle and Tendon
Time Frame: One year
Comparison of changes in biopsies taken before and after interventions between the 3 groups
Genetic Changes in Knee Muscle and Tendon
Time Frame: One year
Comparison of results of genetic testing both before and after interventions between the 3 groups