Effect of magnesium on Nephrotoxicity of Carboplati
Phase 2
- Conditions
- ephrotoxicity of Carboplatin.Nephropathy induced by other drugs, medicaments and biological substancesN14.1
- Registration Number
- IRCT20190619043948N1
- Lead Sponsor
- Arak University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 50
Inclusion Criteria
Children over 2 years of age with malignancy receiving Carboplatin
Exclusion Criteria
Kidney disorder with GFR under 30
Receiving other platinum drugs or other nephrotoxic drugs
Receiving antibiotics
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Blood urea nitrogen. Timepoint: Before intervention and 2 and 7 days later. Method of measurement: Mass spectrometry.;Creatinine. Timepoint: Before intervention and 3 and 7 days later. Method of measurement: Mass spectrometry.;Glomerular filtration rate. Timepoint: Before intervention and 3 and 7 days later. Method of measurement: Schwartz formula, by calculation.
- Secondary Outcome Measures
Name Time Method