IRCT20230930059564N1招募中4 期
Investigating the effect of metformin on vascular function and cardiovascular risk factors in children and adolescents with type 1 diabetes: a randomized, double-blind clinical trial
适应症
试验速览
- 阶段
- 4 期
- 状态
- 招募中
- 入组人数
- 52
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 8 years 至 21 years（—）
- 性别
- All
入选标准
- •Age 8 to 21 years
- •Body mass index (BMI) percentile for ages 5 to 85
- •Receiving insulin (Recombinant, NPH, Regular)
- •Not using metformin in the past year
- •Diagnosis of type 1 diabetes (at least 5 years)
- •Not suffering from diabetic ketoacidosis or hypoglycemia (blood sugar level less than 50 mg/dL) in the last 6 months
- •Not using metformin in the past year
- •Not taking anti-hypertensive, anti-inflammatory, anti-coagulant, fat-reducing, weight-reducing and antioxidant drugs in the last 6 months
- •Willingness to participate in the plan
排除标准
- •Pregnant or lactating people
- •Having severe side effects of metformin (lactic acidosis, severe digestive problems)
- •Suffering from endocrine disorders such as hypothyroidism
- •Any acute illness that leads to hospitalization of the patient
- •Lack of compliance (the patient does not want to continue participating in the study for any reason)
研究者
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