ISRCTN26092132已完成未知
Metformin improves Endothelial function, endothelial progenitor cells and cardiovascular Risk factors In Type 1 diabetes (MERIT study)
Gateshead Health NHS Foundation Trust (UK)0 个研究点目标入组 46 人开始时间: 2012年7月13日最近更新:
适应症
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 发起方
- 入组人数
- 46
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 性别
- All
入选标准
- •1. Type 1 diabetes mellitus
- •2. Aged 16 years or over
- •3. HbA1c <= 8.5
- •4. Duration of diabetes of at least 5 years
- •5. Stable diabetes control for at least 2 months
排除标准
- •1. Glomerular filtration rate (GFR) < 45 ml/ min/ 1.73m2
- •2. Woman of childbearing age planning pregnancy
- •3. Pregnancy and/or lactation
- •4. Proliferative diabetic retinopathy
- •5. Cardiovascular disease/ischemic heart disease (IHD)
- •6. Peripheral vascular disease
- •7. Cerebrovascular accident (CVA) or transient ischemic attack (TIA)
- •8. Suspected hypoglycaemia unawareness
- •9. Impaired cognitive function/ unable to give informed consent
- •10. History of lactic acidosis
- •11. Contraindications to metformin
- •12. History of alcohol problem or drug abuse
研究者
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