Lung Recruitment Improves Right Ventricle Performance
- Conditions
- Atelectasis
- Registration Number
- NCT02795208
- Lead Sponsor
- Hospital Privado de Cordoba, Argentina
- Brief Summary
This study test whether a lung recruitment maneuver improves the right ventricle performance after cardiopulmonary bypass. Half of the patients received an standard protective ventilation and the other half the same ventilatory pattern after a lung recruitment maneuver.
- Detailed Description
Atelectasis is developed in 90% of anesthetized patients after surgery.
Protective ventilation with low tidal volumes and positive-end expiratory pressure (PEEP) promotes atelectasis with the potential right ventricle dysfunction induced by the increment in afterload (activation of the pulmonary hypoxic vasocontriction reflex).
Lung recruitment can improve the right ventricle performance caused by atelectasis because the pulmonary hypoxic vasocontriction reflex desapear in a normal aerated lungs.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 40
- cardiovascular surgery with cardiopulmonary bypass.
- Patients with a New York Heart Association (NYHA) class I-II,
- Pre-operative left ventricular ejection fraction ≥ 50 %.
- Euroscore ≤ 6.
- TEE contraindications.
- Hemodynamically unstable
- Needi for inotropic support
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method Right ventricle assessment by transesophageal echocardiography intraoperative
- Secondary Outcome Measures
Name Time Method Atelectasis assessment by transesophageal echocardiography intraoperative PaO2 and respiratory compliance intraoperative