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Lung Recruitment Improves Right Ventricle Performance

Not Applicable
Completed
Conditions
Atelectasis
Registration Number
NCT02795208
Lead Sponsor
Hospital Privado de Cordoba, Argentina
Brief Summary

This study test whether a lung recruitment maneuver improves the right ventricle performance after cardiopulmonary bypass. Half of the patients received an standard protective ventilation and the other half the same ventilatory pattern after a lung recruitment maneuver.

Detailed Description

Atelectasis is developed in 90% of anesthetized patients after surgery.

Protective ventilation with low tidal volumes and positive-end expiratory pressure (PEEP) promotes atelectasis with the potential right ventricle dysfunction induced by the increment in afterload (activation of the pulmonary hypoxic vasocontriction reflex).

Lung recruitment can improve the right ventricle performance caused by atelectasis because the pulmonary hypoxic vasocontriction reflex desapear in a normal aerated lungs.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
40
Inclusion Criteria
  • cardiovascular surgery with cardiopulmonary bypass.
  • Patients with a New York Heart Association (NYHA) class I-II,
  • Pre-operative left ventricular ejection fraction ≥ 50 %.
  • Euroscore ≤ 6.
Exclusion Criteria
  • TEE contraindications.
  • Hemodynamically unstable
  • Needi for inotropic support

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Primary Outcome Measures
NameTimeMethod
Right ventricle assessment by transesophageal echocardiographyintraoperative
Secondary Outcome Measures
NameTimeMethod
Atelectasis assessment by transesophageal echocardiographyintraoperative
PaO2 and respiratory complianceintraoperative

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