ithium for mild-to-moderate Alzheimer's disease: A randomized double-blind, placebo-controlled study

Iwata Nakao0 个研究点目标入组 46 人开始时间: 2019年1月29日最近更新: 2023年10月17日

适应症

试验速览

阶段: 2 期
状态: 已完成
发起方
入组人数: 46

研究概览入排标准研究者记录与标识符相似试验

研究概览

简要总结

The results of this study showed that lithium was not effective for Alzheimer's disease. In terms of safety, lithium did not show a statistically significant difference in the placebo group. The main limitation of the study is the lack of power due to failure to reach the target number of cases.

研究设计

研究类型: Interventional

入排标准

年龄范围: none 至 none（—）
性别: All

入选标准

•(1) The patient meets Diagnostic and Statistical Manual of Mental Disorders-V probable Alzheimer's disease.
•(2) Clinical Dementia Rating scores are 1 or 2 points.

排除标准

•(1)Patients complicated of dementia other than Alzheimer's disease.
•(2)Patients with a history of drug hypersensitivity to lithium.
•(3)Lithium carbonate administration is contraindicated.
•(4)Patients with severe complications and poor management.
•(5)Patients with renal dysfunction (creatinine clearance <30).

研究者

发起方

Iwata Nakao

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