Multi-center Research Project for Glioma Molecular Pathology Intraoperative Rapid Detection

Completed

• Conditions: Glioma, Malignant

• Registration Number: NCT04904419
• Lead Sponsor: Jinsong Wu

Brief Summary

We explores the accuracy and sensitivity of rapid intraoperative detection of IDH, TERT, BRAF indicators through a prospective clinical multi-center study. This part includes a total of 300 fresh tissue samples, paired blood samples, relevant clinical information and follow-up information from 300 patients with different grades of adult glioma. By comparing with the postoperative sequencing results, the specificity and sensitivity of intraoperative IDH and TERT rapid detection results are clear.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2021-05-23
• Study First Submitted QC: 2021-05-23
• Study First Posted: 2021-05-27
• Study Start: 2021-08-01
• Primary Completion: 2022-01-31
• Study Completion: 2022-01-31
• Status Verified: 2023-04
• Last Update Submitted: 2023-04-14
• Last Update Posted: 2023-04-18

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 137

Inclusion Criteria

• 1. Glioma patients with Informed Consent Form 2. Glioma patients with intact clinical information

Exclusion Criteria

• 1. Glioma patients without Informed Consent Form 2. Glioma patients without intact clinical information

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Intraoperative Rapid Detection mutation of IDH, TERT and BRAF v600e	Intraoperative Rapid Detection mutation of IDH, TERT and BRAF v600e

Trial Locations

Locations (4)

The First Affiliated Hospital of Fujian Medical University; 🇨🇳 Fuzhou, China

Huashan Hospital; 🇨🇳 Shanghai, China

Huashan Hospital(West campus); 🇨🇳 Shanghai, China

General Hospital of Ningxia Medical University; 🇨🇳 Yinchuan, China