To evaluate the role of intralesional bleomycin in cases of capillary hemangioma unresponsive to oral propranolol

Phase 2

Not yet recruiting

• Conditions: Other specified disorders of eyelid, (2) ICD-10 Condition: O||Medical and Surgical,

• Registration Number: CTRI/2023/08/056626
• Lead Sponsor: Rp center institute of ophthalmic sciences

Brief Summary

Prospective interventional study to evaluate the role of intralesional bleomycin in patients of periocular hemangiomas unresponsive to oral propranolol .since surgery , corticosteroids and radiation therapy has side effects.Currently there is paucity of prospective interventional studies regarding the same.Retrospective studies showed benefit of the intralesional bleomycin injections

Detailed Description

Not available

Study Timeline

• Last Update Posted: 2023-08-17
• Study Start: 2023-08-30

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 10

Inclusion Criteria

All periocular capillary hemangioma patients 0-18 years who are resistant to oral propranolol.

Exclusion Criteria

Age > 18 years Capillary hemangioma responding to oral propranolol.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Comparing the area of the lesion , maximum horizontal diameter , maximum vertical diameter , color change , percentage of area reduction	At baseline , 1 week , 4 weeks , 2 months , 3 months and 6 months

Secondary Outcome Measures

Name	Time	Method
Change in BCVA , percentage reduction in area	2 weeks , 1 month , 3 months , 6 months

Trial Locations

Locations (1)

All india institute of medical sciences , Delhi; 🇮🇳 Central, DELHI, India

All india institute of medical sciences , Delhi

🇮🇳Central, DELHI, India

Dr MSbajaj

Principal investigator

7838661654

Msbajaj32@hotmail.com