CTRI/2021/01/030533尚未招募未知
Sildenafil Use in Covid-19 Patients - A Pilot Study
Sardar Vallabh Bhai Patel Covid Hospital0 个研究点目标入组 0 人开始时间: 待定最近更新:
试验速览
- 阶段
- 未知
- 状态
- 尚未招募
- 发起方
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
入选标准
- •1.Established case of Covid-19 (RTPCR +ve)
- •2.Moderate Covid-19 patients (SpO2 90 â?? 94% on room air, RR 24 â?? 30/min) with visible radiographic features of pneumonia
- •3.Severe Covid-19 patients (SpO2 < 90% on room air, RR >30/min) with visible radiographic features of pneumonia
排除标准
- •1.Pregnant and lactating women
- •2.Patients on Nitrate medications in any form
- •3.Patients with any malignant tumor
- •4.Patients with heart ailments including Myocardial Infarction (in < 6 months) or heart failure.
- •5.Patients with mental illness or stroke ( < 6months)
- •6.Advanced liver or kidney ailment
- •7.Patients with known history of severe systemic hypertension especially if uncontrolled
- •8.Patients with systemic hypotension because of any reason.
- •9.Patients allergic to Sildenafil
- •10.Patients already on mechanical ventilation
- •11.Patients with inability to take drug orally or inability to place Ryleâ??s tube.
研究者
相似试验
Unknown
3 期
A Pilot Study of Sildenafil in COVID-19COVID-19NCT04304313Tongji Hospital10
已完成
1 期
Sildenafil in COVID-19Covid19SARS-COV2 InfectionNCT04489446Universidad Nacional Andres Bello40
尚未招募
不适用
Pilot Study assessing sildenafil effect on lung tumour blood flownon-small cell lung cancerlung cancer10038666NL-OMON31434Vrije Universiteit Medisch Centrum10
进行中（未招募）
不适用
Pilot of oral Sildenafil for the treatment of Pulmonary Hypertension in Thalassaemia with comparison to controls. - Pulmonary Hypertension (PHT)StudyPulmonary Hypertension in Thalassaemia patientsEUCTR2009-016096-29-GBniversity College London24
进行中（未招募）
不适用
Application of Sildenafil in patients with documented coronary vasospasm in order to explore the pathophysiology of coronary vasospasm and the therapeutic effects of Sildenafil in patients suffering from coronary spasmCoronary vasospasm is an abrupt severe vasoconstriction of coronary arteries leading to myocardial ischemia and angina pectoris. The reason for the occurrence of coronary spasm and the cellular mechanism causing coronary spasm is still not elucidated. Thus, an appropriate medical therapy has not been established so far. In patients suffering from coronary vasospasm the possible anti-spastic effect of sildenafil is to be analysed with this study.EUCTR2006-003116-22-DEProf. Sechtem, Department of Cardiology, Robert Bosch Hospital