Tumor cells in pleural effusion and peripheral blood of malignant pleural mesothelioma patients

Completed

• Conditions: maligant pleural mesothelioma; malignant mesothelioma; 10027412

• Registration Number: NL-OMON40425
• Lead Sponsor: Erasmus MC, Universitair Medisch Centrum Rotterdam

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 11 June 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 60

Inclusion Criteria

- Age ><=18 years
- Patient requiring a pleural drainage or VATS as a part of standard care
- High clinical suspicion of the presence of pleural effusion
- Written informed consent

Exclusion Criteria

None

Study & Design

• Study Type: Observational non invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Verdict of pleural effusion analysis (negative for MPM, suspicious for MPM or<br /><br>positive for MPM) by PTC enumeration versus cytological analysis. </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>- Number of CTCs<br /><br>- Number of CECs<br /><br>- Number of immune cells<br /><br>- Overall survival</p><br>