Cardiovascular Benefits of Acai Polyphenols in Volunteers at Risk of Metabolic Syndrome
Not Applicable
Completed
- Conditions
- Cardiovascular Diseases
- Interventions
- Dietary Supplement: Acai puree, frozen blended it with bananaDietary Supplement: Control Macronutrient matched
- Registration Number
- NCT02292329
- Lead Sponsor
- University of Reading
- Brief Summary
The purpose of this study is to carry out a randomized double blind controlled trial in 30 male subjects to investigate the effect of acai consumption on acute changes in vascular function, and to other cardiovascular markers. As a secondary aim the study will allow us to characterize the absorption and metabolism of acai polyphenols in humans over a 24 hour period.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- Male
- Target Recruitment
- 23
Inclusion Criteria
- Male, 30-65 aged, BMI 25-35 kg/m2, Cholesterol <8 mmol/l.
Exclusion Criteria
- Female, BMI <25 or >35 kg/m2, Cholesterol >8mmol l-1, elevated fasting blood sugar > 6.5 mmols l-1 , elevated systolic blood pressure >150 mmHg, history of stroke or heart attack within the previous 12 months, current smoking, taking lipid lowering, blood pressure lowering or anti-blood clotting medication or taking micronutrient supplements.
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- CROSSOVER
- Arm && Interventions
Group Intervention Description 150g of acai fruit Acai puree, frozen blended it with banana 150g of acai fruit in fruit smoothie form Placebo control Control Macronutrient matched The control will be a smoothie-like drink matched for major macro- and micro-nutrients
- Primary Outcome Measures
Name Time Method Flow-mediated dilation Change from baseline to 2h
- Secondary Outcome Measures
Name Time Method plasma polyphenol metabolites Change from baseline to 24h
Trial Locations
- Locations (1)
Hugh Sinclair Unit of Human Nutrition
🇬🇧Reading, Berkshire, United Kingdom