Adapting Project UPLIFT (Using Practice and Learning to Increase Favorable Thoughts) is for Hispanic Patients With Epilepsy II
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- NYU Langone Health
- Enrollment
- 72
- Locations
- 1
- Primary Endpoint
- Patient Health Questionnaire (PHQ-9)
Study Overview
Brief Summary
The purpose of this study is to adapt Project UPLIFT for Hispanic adults with epilepsy and depression. Project UPLIFT (Using Practice and Learning to Increase Favorable Thoughts) is a home-based intervention that teaches cognitive and mindfulness skills to people with epilepsy by phone to reduce their depression and improve quality of life (QOL); it was developed at Emory University with CDC funding. The purpose of this study is to adapt Project UPLIFT for Hispanic adults with epilepsy and depression. Project UPLIFT (Using Practice and Learning to Increase Favorable Thoughts) is a home-based intervention that teaches cognitive and mindfulness skills to people with epilepsy by phone to reduce their depression and improve quality of life (QOL); it was developed at Emory University with CDC funding.
Detailed Description
The goal of this study is to adapt Project UPLIFT for Hispanic adults with epilepsy and depression. A 2-arm randomized control trial will be conducted to evaluate the feasibility, acceptability and effects of Project UPLIFT versus usual care (UC) in Hispanic patients with epilepsy.
The specific aim of this study is: To evaluate the feasibility, acceptability and short- and long-term effects of the adapted intervention on depression and other outcomes in 72 English- and Spanish-speaking Hispanic epilepsy patients.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Parallel
- Primary Purpose
- Treatment
- Masking
- Single (Outcomes Assessor)
Eligibility Criteria
- Ages
- 21 Years to — (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- •self-identified as Hispanic
- •English or Spanish speaking
- •diagnosis of epilepsy for at least one year post diagnosis
- •willing to participate in 8 one-hour telephone sessions every week for eight weeks.
- •willing to be audio-taped
- •Elevated depressive symptoms (Center for Epidemiological Studies Depression Scale (CES-D) score >13
Exclusion Criteria
- •Severe depression (CES-D > 37)
- •Active suicidal ideation
- •Significant cognitive impairment (evident during screening)
Outcomes
Primary Outcomes
Patient Health Questionnaire (PHQ-9)
Time Frame: 12 Months
This measure assesses depressive symptoms in the past two weeks based on DSM-IV diagnostic criteria for major depression.
Secondary Outcomes
- Quality Of Life in Epilepsy (QOLIE-10)(12 Months)
- PROMIS-Global(12 Months)