The effects of plant stanols on the immune function of asthma patients
Recruiting
- Conditions
- allergyAsthma1000170810038716
- Registration Number
- NL-OMON36451
- Lead Sponsor
- niversiteit Maastricht
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 90
Inclusion Criteria
Asthma Age between 18 and 70 Men and women Specific anti-hepatitis A virus antibody titers < 20 IU/L
Exclusion Criteria
- Current asthmatic exacerbations, i.e. use of prednisone or pneumoia - Other immune-related pathology, e.g. autoimmune diseases, diabetes, HTLV, HIV, other inflammatory diseases than asthma. - Previously being vaccinated against hepatitis A - Pregnancy or lactation - Impaired liver and kidney function - Use of immunosuppressive medication - Allergy to neomycin - Throbocytopenia
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>Specific anti-HAV antibody titers after vaccination </p><br>
- Secondary Outcome Measures
Name Time Method <p>Phagocytic capacity of neutrophils; NK-cell activity; Th1 and Th2 cytokine<br /><br>production profiles by PHA stimulated PMBCs. </p><br>