Cigarette and E-cigarette Flavors Manipulations in the Experimental Tobacco Marketplace

Not Applicable

Completed

• Conditions: Tobacco Use Disorder
• Interventions: Behavioral: Cigarette flavor restricted and e-cigarette flavor restricted; Behavioral: Cigarette flavor restricted and e-cigarette flavor unrestricted; Behavioral: Cigarette flavor unrestricted and e-cigarette flavor restricted; Behavioral: Cigarette flavor unrestricted and e-cigarette flavor unrestricted

• Registration Number: NCT05110872
• Lead Sponsor: Virginia Polytechnic Institute and State University

Brief Summary

This is a one-session study that participants complete remotely including consent, Experimental Tobacco Marketplace purchases, and assessments to examine the effects of cigarette and e-cigarette flavors on cigarette demand and substitution in the Experimental Tobacco Marketplace.

Detailed Description

This study uses a mixed design (within-subject repeated measures and between-group). Participants will be assigned to two different groups according to their preferred cigarette flavor (tobacco/menthol). Every participant will complete behavioral tasks and make hypothetical purchases of tobacco products in an online store under four different scenarios: a) e-cigarette flavor restricted and cigarette flavor restricted, b) e-cigarette flavor unrestricted and cigarette flavor restricted, c) e-cigarette flavor restricted and cigarette flavor unrestricted, d) e-cigarette flavor unrestricted and cigarette flavor unrestricted.

Study Timeline

• Study Start: 2021-07-26
• Primary Completion: 2021-08-13
• Study Completion: 2021-08-13
• Study First Submitted: 2021-10-11
• Study First Submitted QC: 2021-10-26
• Study First Posted: 2021-11-08
• Status Verified: 2022-01
• Last Update Submitted: 2022-01-27
• Last Update Posted: 2022-02-11

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 307

Inclusion Criteria

• currently smoke at least 10 cigarettes per day
• have smoked at least 100 cigarettes (lifetime), and
• are 21 years of age or older.

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Exclusion Criteria

• inaccurate identification of usual brand of cigarette's as menthol or non-menthol

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Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Arm && Interventions

Group	Intervention	Description
Menthol cigarette smokers	Cigarette flavor restricted and e-cigarette flavor unrestricted	Adults (21 y.o. and older) who smoke ate least 10 menthol cigarettes per day will be recruited.
Menthol cigarette smokers	Cigarette flavor restricted and e-cigarette flavor restricted	Adults (21 y.o. and older) who smoke ate least 10 menthol cigarettes per day will be recruited.
Menthol cigarette smokers	Cigarette flavor unrestricted and e-cigarette flavor unrestricted	Adults (21 y.o. and older) who smoke ate least 10 menthol cigarettes per day will be recruited.
Non-menthol cigarette smokers	Cigarette flavor restricted and e-cigarette flavor unrestricted	Adults (21 y.o. and older) who smoke ate least 10 non-menthol cigarettes per day will be recruited.
Menthol cigarette smokers	Cigarette flavor unrestricted and e-cigarette flavor restricted	Adults (21 y.o. and older) who smoke ate least 10 menthol cigarettes per day will be recruited.
Non-menthol cigarette smokers	Cigarette flavor restricted and e-cigarette flavor restricted	Adults (21 y.o. and older) who smoke ate least 10 non-menthol cigarettes per day will be recruited.
Non-menthol cigarette smokers	Cigarette flavor unrestricted and e-cigarette flavor unrestricted	Adults (21 y.o. and older) who smoke ate least 10 non-menthol cigarettes per day will be recruited.
Non-menthol cigarette smokers	Cigarette flavor unrestricted and e-cigarette flavor restricted	Adults (21 y.o. and older) who smoke ate least 10 non-menthol cigarettes per day will be recruited.

Primary Outcome Measures

Name	Time	Method
E-cigarette substitution	1 day	Participants will complete purchasing trials in an Experimental Tobacco Marketplace (ETM) with cigarettes increasing in price. Product availability in the ETM depended on the experimental condition. The degree to which e-cigarettes substitute for conventional cigarettes as a function of cigarettes and e-cigarettes restriction will be assessed.; To obtain estimates of substitution of price-constant products in the different ETM conditions, the investigators will use ordinary least squares regression to model the relationship of the price-manipulated product to predict total quantity purchased of the price-constant product.
Cigarette demand	1 day	Participants will complete purchasing trials in an Experimental Tobacco Marketplace (ETM) with cigarettes increasing in price. Product availability in the ETM depended on the experimental condition. The degree to which cigarette and e-cigarette restrictions influence demand for conventional cigarettes will be assessed.; To obtain dependent measures of demand, participants' purchasing of the price-manipulated commodity in the ETM task will be fit to a modified exponential equation to quantify the relationship between the price of each commodity and purchasing: Q=Q0\*10k(exp(-αQ0C)-1) where Q is purchasing of the commodity, C is the price, Q0 is the derived initial purchasing without cost constraints (demand intensity), k is the span of the function in logarithmic units, and α is the demand elasticity.

Trial Locations

Locations (1)

Fralin Biomedical Research Institute; 🇺🇸 Roanoke, Virginia, United States