Cigarette and E-cigarette Flavors Manipulations in the Experimental Tobacco Marketplace

Not Applicable

Completed

• Conditions: Tobacco Use Disorder

• Registration Number: NCT05110872
• Lead Sponsor: Virginia Polytechnic Institute and State University

Brief Summary

This is a one-session study that participants complete remotely including consent, Experimental Tobacco Marketplace purchases, and assessments to examine the effects of cigarette and e-cigarette flavors on cigarette demand and substitution in the Experimental Tobacco Marketplace.

Detailed Description

This study uses a mixed design (within-subject repeated measures and between-group). Participants will be assigned to two different groups according to their preferred cigarette flavor (tobacco/menthol). Every participant will complete behavioral tasks and make hypothetical purchases of tobacco products in an online store under four different scenarios: a) e-cigarette flavor restricted and cigarette flavor restricted, b) e-cigarette flavor unrestricted and cigarette flavor restricted, c) e-cigarette flavor restricted and cigarette flavor unrestricted, d) e-cigarette flavor unrestricted and cigarette flavor unrestricted.

Study Timeline

• Study Start: 2021-07-26
• Primary Completion: 2021-08-13
• Study Completion: 2021-08-13
• Study First Submitted: 2021-10-11
• Study First Submitted QC: 2021-10-26
• Study First Posted: 2021-11-08
• Status Verified: 2025-09
• Results First Submitted: 2025-09-03
• Results First Submitted QC: 2025-09-23
• Last Update Submitted: 2025-09-23
• Results First Posted: 2025-10-07
• Last Update Posted: 2025-10-07

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 302

Inclusion Criteria

• currently smoke at least 10 cigarettes per day
• have smoked at least 100 cigarettes (lifetime), and
• are 21 years of age or older.

Exclusion Criteria

• inaccurate identification of usual brand of cigarette's as menthol or non-menthol

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Primary Outcome Measures

Name	Time	Method
Spent the Budget on E-cigarettes for Each Condition	1 day	Participants will complete purchasing trials in an Experimental Tobacco Marketplace (ETM) with cigarettes increasing in price. Product availability in the ETM depended on the experimental condition. The average percentage of budget spent on e-cigarettes as a function of the restriction of cigarettes and/or e-cigarettes will be assessed.
Spent Budget on Cigarettes for Each Condition	1 day	Participants will complete purchasing trials in an Experimental Tobacco Marketplace (ETM) with cigarettes increasing in price. Product availability in the ETM depended on the experimental condition. The average percentage of the budget spent on cigarettes as a function of the restriction of cigarettes and/or e-cigarettes will be assessed.

Trial Locations

Locations (1)

Fralin Biomedical Research Institute; 🇺🇸 Roanoke, Virginia, United States