DEVELOPMENT OF NOVEL DISINFECTANT SKINPATCH FOR BLOOD DONORS PHLEBOTOMY
Trial Snapshot
- Phase
- Phase 3
- Status
- Not yet recruiting
- Sponsor
- Enrollment
- 50
- Locations
- 1
- Primary Endpoint
- Antibacterial and antiseptic effect on the phlebotomy sites.
Study Overview
Brief Summary
The study plan is to develop a novel disinfectant patch which uses the disinfectant properties of nanoparticles. The nanoparticles which is being developed are nanoparticles composites of BG-AgrGO/PCL (bioglass-silver functionalized reduced graphene oxide/polycaprolactone) , AgBG-GO/PCL (Ag doped bioglass-graphene oxide/polycaprolactone) & AgBG-rGO/PCL (Ag doped bioglass-reduced graphene oxide/polycaprolactone). The above mentioned composites are being used in the developed dermal patches.
The presence of silver will give the antibacterial activity along with the Graphene oxides, both acting against the bacterial cell walls. the reduced graphene oxides with silver should exhibit better antibacterial activity for prolonged duration of time and effectiveness. The dermal patch will be evaluated for their bioactivity and antibacterial properties, followed by its utilisation in the disinfectant purposes for phlebotomy. The dermal patch will be convenient and more effective as compared to currently practiced disinfectant procedures. This product will be tested in the animal study following which the same will be undergoing human trials.
Study Design
- Study Type
- Interventional
- Allocation
- Coin toss, Lottery, toss of dice, shuffling cards etc
- Masking
- Participant Blinded
Eligibility Criteria
- Ages
- 18.00 Year(s) to 50.00 Year(s) (—)
- Sex
- All
Inclusion Criteria
- •HEALTHY INDIVIDUALS WITH NO COMORBIDITIES.
- •NO HISTORY OF DRUG OR SKIN ALLERGIES.
Exclusion Criteria
- •INDIVIDUALS WITH BROKEN SKIN OVER CUBITAL REGIONS.
Outcomes
Primary Outcomes
Antibacterial and antiseptic effect on the phlebotomy sites.
Time Frame: 10 minutes.
Secondary Outcomes
- Lesser incidences of bacterial contamination of collected blood.(10 minutes.)
Investigators
VIJIT JOON
Saveetha Medical College