Evaluating the antibacterial effects of widely available Green tea, Chamomile tea and Moringa tea on salivary Streptococcus Mutans Level: An in vivo Study
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- The primary outcome of this study is the change in the salivary Streptococcus mutans count from baseline to post-intervention, measured quantitatively after the participants have consumed the assigned tea intervention for the specified study duration.
研究概览
简要总结
This in vivo study aims to evaluate and compare the antibacterial effects of three commonly available herbal teas—Green tea, Chamomile tea, and Moringa tea in comparison to Chlorhexidine gluconate on the salivary levels of Streptococcus mutans, a primary contributor to dental caries. Healthy participants will be randomly assigned to one of the four intervention groups each consuming a specified quantity of the assigned tea daily over a fixed period. Unstimulated saliva samples will be collected at baseline and post-intervention to quantify changes in S. mutans using qPCR (Real time Polymerase chain reaction) technique for each participant. . The study seeks to identify which of the three herbal teas demonstrates the most effective reduction in salivary S. mutans levels, potentially contributing to the development of natural, preventive oral health strategies.
研究设计
- 研究类型
- Interventional
- 分配方式
- Coin toss, Lottery, toss of dice, shuffling cards etc
- 盲法
- Participant and Outcome Assessor Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 24.00 Year(s)（—）
- 性别
- All
入选标准
- •1.Participants not consuming these herbal tea prior to study.
- •2.Not associated with any systemic disease.
- •3.No history of receiving fluoride mouthwash or varnish for at least one month before sampling.
排除标准
- •1.Those undergoing antibiotic therapy.
- •2.Presence of rampant caries, soft tissue lesions, and localized/ generalized active periodontitis.
- •3.History of usage of any medication or antimicrobial mouthwash like CHG and participants who had prosthetic-orthodontic appliances.
结局指标
主要结局
The primary outcome of this study is the change in the salivary Streptococcus mutans count from baseline to post-intervention, measured quantitatively after the participants have consumed the assigned tea intervention for the specified study duration.
时间窗: Baseline (Day 0 – before intervention) | 1 Week post-intervention | 1 Month post-intervention | 6 Months post-intervention | 1 Year post-intervention
次要结局
未报告次要终点
研究者
Paras
Faculty of Dental Sciences, SGT University, Gurugram