DEVELOPMENT OF NOVEL DISINFECTANT SKINPATCH FOR BLOOD DONORS PHLEBOTOMY
试验速览
- 阶段
- 3 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 50
- 试验地点
- 1
- 主要终点
- Antibacterial and antiseptic effect on the phlebotomy sites.
研究概览
简要总结
The study plan is to develop a novel disinfectant patch which uses the disinfectant properties of nanoparticles. The nanoparticles which is being developed are nanoparticles composites of BG-AgrGO/PCL (bioglass-silver functionalized reduced graphene oxide/polycaprolactone) , AgBG-GO/PCL (Ag doped bioglass-graphene oxide/polycaprolactone) & AgBG-rGO/PCL (Ag doped bioglass-reduced graphene oxide/polycaprolactone). The above mentioned composites are being used in the developed dermal patches.
The presence of silver will give the antibacterial activity along with the Graphene oxides, both acting against the bacterial cell walls. the reduced graphene oxides with silver should exhibit better antibacterial activity for prolonged duration of time and effectiveness. The dermal patch will be evaluated for their bioactivity and antibacterial properties, followed by its utilisation in the disinfectant purposes for phlebotomy. The dermal patch will be convenient and more effective as compared to currently practiced disinfectant procedures. This product will be tested in the animal study following which the same will be undergoing human trials.
研究设计
- 研究类型
- Interventional
- 分配方式
- Coin toss, Lottery, toss of dice, shuffling cards etc
- 盲法
- Participant Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 50.00 Year(s)(—)
- 性别
- All
入选标准
- •HEALTHY INDIVIDUALS WITH NO COMORBIDITIES.
- •NO HISTORY OF DRUG OR SKIN ALLERGIES.
排除标准
- •INDIVIDUALS WITH BROKEN SKIN OVER CUBITAL REGIONS.
结局指标
主要结局
Antibacterial and antiseptic effect on the phlebotomy sites.
时间窗: 10 minutes.
次要结局
- Lesser incidences of bacterial contamination of collected blood.(10 minutes.)
研究者
VIJIT JOON
Saveetha Medical College
