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临床试验/CTRI/2024/12/078388
CTRI/2024/12/078388尚未招募3 期

DEVELOPMENT OF NOVEL DISINFECTANT SKINPATCH FOR BLOOD DONORS PHLEBOTOMY

Vijit Joon1 个研究点 分布在 1 个国家目标入组 50 人开始时间: 2025年1月1日最近更新:

试验速览

阶段
3 期
状态
尚未招募
发起方
入组人数
50
试验地点
1
主要终点
Antibacterial and antiseptic effect on the phlebotomy sites.

研究概览

简要总结

The study plan is to develop a novel disinfectant patch which uses the disinfectant properties of nanoparticles. The nanoparticles which is being developed are  nanoparticles composites of BG-AgrGO/PCL (bioglass-silver functionalized reduced graphene oxide/polycaprolactone) , AgBG-GO/PCL (Ag doped bioglass-graphene oxide/polycaprolactone) & AgBG-rGO/PCL (Ag doped bioglass-reduced graphene oxide/polycaprolactone). The above mentioned composites are being used in the developed dermal patches.

The presence of silver will give the antibacterial activity along with the Graphene oxides, both acting against the bacterial cell walls. the reduced graphene oxides with silver should exhibit better antibacterial activity for prolonged duration of time and effectiveness. The dermal patch will be evaluated for their bioactivity and antibacterial properties, followed by its utilisation in the disinfectant purposes for  phlebotomy. The dermal patch will be convenient and more effective as compared to currently practiced disinfectant procedures. This product will be tested in the animal study following which the same will be undergoing human trials.

研究设计

研究类型
Interventional
分配方式
Coin toss, Lottery, toss of dice, shuffling cards etc
盲法
Participant Blinded

入排标准

年龄范围
18.00 Year(s) 至 50.00 Year(s)(—)
性别
All

入选标准

  • HEALTHY INDIVIDUALS WITH NO COMORBIDITIES.
  • NO HISTORY OF DRUG OR SKIN ALLERGIES.

排除标准

  • INDIVIDUALS WITH BROKEN SKIN OVER CUBITAL REGIONS.

结局指标

主要结局

Antibacterial and antiseptic effect on the phlebotomy sites.

时间窗: 10 minutes.

次要结局

  • Lesser incidences of bacterial contamination of collected blood.(10 minutes.)

研究者

发起方
Vijit Joon
申办方类型
Other [self]
责任方
Principal Investigator
主要研究者

VIJIT JOON

Saveetha Medical College

研究点 (1)

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