Asthma Reduction with Inhaled corticoSteroids in Children with a high risk for the development of asthma (At RISC)

Completed

• Conditions: Asthma; Respiratory

• Registration Number: ISRCTN58244066
• Lead Sponsor: Care and Public Health Research Institute (CAPHRI), University Maastricht (Netherlands)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2006-01-27
• Last Update Posted: 13 January 2015

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 97

Inclusion Criteria

1. Male and female patients aged 1-4.5 years with a familial predisposition for asthma in the first degree, who have experienced at least 2 separate periods with wheeze lasting at least 2 days each documented by their general practitioner
2. For each patient who enters the study a written informed consent by the parent or guardian of the patient should be obtained

Exclusion Criteria

1. Patients who have been treated with pulmonary anti-inflammatory inhaled drugs for more than 2 weeks or anti-inflammatory oral drugs for more than 1 week preceding the study
2. Patients who have been hospitalised for asthma in the 2 weeks prior to the study
3. Patients who have serious respiratory morbidity (e.g. broncho-pulmonary dysplasia, cystic fibrosis, tuberculosis)
4. Patients, who have laboratory or clinical evidence of serious uncontrolled systemic disease (as judged by the investigator)
5. Patients with anatomical abnormalities of the upper airways or lungs
6. Patients currently participating in another drug intervention study
7. When the general practitioner considers it detrimental to the patient to participate in the study

Study & Design

• Study Type: Interventional
• Study Design: Not specified