Poor Quality of Life Associated With Traditional Chinese Medicine Constitution in HIV-infected Men Who Have Sex With Men
- Conditions
- HIV InfectionsQuality of Life
- Interventions
- Diagnostic Test: World Health Organization Quality of Life -Brief -Taiwan version (WHOQOL-BREF-Taiwan version)
- Registration Number
- NCT05299775
- Lead Sponsor
- Taipei City Hospital
- Brief Summary
This study explores the pathological constitution as it relates to low quality of life with HIV- infected MSM patients, as a reference for clinical treatment.
- Detailed Description
Introduction :This study explores the pathological constitution as it relates to low quality of life with HIV- infected MSM patients, as a reference for clinical treatment.
Methods :It has a cross-sectional research design using structured questionnaires to collect data,including patient's basic case data, CD4+, CD4+/CD8+ ratio, Wang Qi constitution and WHOQOL-BREF -Taiwan version questionnaires. We consider the association between the constitutions and quality of life for HIV-infected MSM patients.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- Male
- Target Recruitment
- 203
- Patients diagnosed with HIV infected.
- Age greater than 20 years old (including) and less than 60 years old.
- Conscious clear and voluntary to attend the project with agreement.
- Willing to fill out the informed consent form.
- conscious unclear
- Patients had histories of severe psychiatric disorders ( ex: schizophrenia) or if they met the criteria of Diagnostic and Statistical Manual of Mental Disorders ( ex: dementia)
- Age < 20 years old.
- The patient does not want to fill out the informed consent form for any reason.
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description HIV infected time World Health Organization Quality of Life -Brief -Taiwan version (WHOQOL-BREF-Taiwan version) Group are divided by Infected time: 0-2W, 2W-12M, \>1Y
- Primary Outcome Measures
Name Time Method quality of life score Lasts for 1 year investigate different quality of life score of HIV infected time in the physical,psychological, social, and environmental domains.
Outcome Measure:4 quality of life scores for each constitution ， In the WHOQOL-BREF Taiwan item scores range from 1 (worst condition) to 5 (best condition), except for 3 items (Ph1, Ph2, and Ps6), which have reverse scores. Two scales (0-100 and 4-20, with a higher score indicating better QOL) can be transformed into domain scores for each domain and we used the 4-20 scale in this study,Add the item scores for each domain ,the higher scores indicating better quality of lifeTCM constitution Lasts for 1 year Investigate TCM constitution composed of HIV-infected in yang deficiency , yin deficiency , qi deficiency , phlegm dampness , damp-heat , blood stasis , special diathesis , qi stagnation , and gentleness constitution .
Outcome Measure:Nine kinds TCM constitution-the constitution type must be judged according to the standards. Original score = sum of the scores of items for each constitution, and then the original score is converted into a conversion score \[conversion score = \[(original score-number of answer items) / answer items × 4\] × 100.
Judgment of constitutions: gentleness is a normal constitution, and others are pathological constitutions. Gentleness constitution conversion score ≥ 60 points, and other pathological constitution conversion score \<30 points, it is Gentleness constitution; pathological constitution conversion score ≥ 40 is considered pathological constitution, The higher the conversion score is the more obvious the constitution trend
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Taipei City Hospital
🇨🇳Taipei, Taiwan