The Efficacy and Safety of Beta-blockers Drugs in Adults With Spinal Hemangioma
Phase 4
- Conditions
- Spinal HemangiomaSpinal TumorBeta Blocker Toxicity
- Interventions
- Registration Number
- NCT05106179
- Lead Sponsor
- Center for Vascular Pathology, Moscow
- Brief Summary
Spinal hemangioma is one of the most common benign vertebral tumours. Being mostly asymptomatic, it is still associated with a pain syndrome especially if encroaches into the neural canal.
This study is organised to evaluate the efficacy and safety of β-blockers drugs in adults with spinal hemangioma.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 1000
Inclusion Criteria
- vertebral hemangioma
Exclusion Criteria
- symptomatic bradycardia
- AV block
- decompensated heart failure
- asthma
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Previously treated + Atenolol Atenolol Pill The investigators suppose the outcome might be compromised if patient has been previously treated, that's why it is going to be compared to the main cohort. The results are going to be analysed separately Previously treated + Propranolol Propranolol Pill The investigators suppose the outcome might be compromised if patient has been previously treated, that's why it is going to be compared to the main cohort. The results are going to be analysed separately
- Primary Outcome Measures
Name Time Method Reducing tumor 6 months MRI
Reducing tumor growth 3 months MRI
Life-quality 3 months and 6 months Valid questionnaires based on the ones, approved by EuroQol Organization
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
The Vascular Anomalies Center (VAC) "Hemangioma"
🇷🇺Moscow, Russian Federation