Propranolol
- Generic Name
- Propranolol
- Brand Names
- Hemangeol, Hemangiol, Inderal, Innopran
- Drug Type
- Small Molecule
- Chemical Formula
- C16H21NO2
- CAS Number
- 525-66-6
- Unique Ingredient Identifier
- 9Y8NXQ24VQ
- Background
Propranolol is a racemic mixture of 2 enantiomers where the S(-)-enantiomer has approximately 100 times the binding affinity for beta adrenergic receptors. Propranolol is used to treat a number of conditions but most commonly is used for hypertension.
Propranolol was granted FDA approval on 13 November 1967.
- Indication
Propranolol is indicated to treat hypertension. Propranolol is also indicated to treat angina pectoris due to coronary atherosclerosis, atrial fibrillation, myocardial infarction, migraine, essential tremor, hypertrophic subaortic stenosis, pheochromocytoma, and proliferating infantile hemangioma.
- Associated Conditions
- Akathisia caused by antipsychotic use, Angina Pectoris, Atrial Fibrillation, Cardiovascular Mortality, Essential Tremor, Gastroesophageal variceal hemorrhage prophylaxis, Hemangiomas, Hypertension, Migraine, Myocardial Infarction, Obstructive Hypertrophic Cardiomyopathy, Performance Anxiety, Pheochromocytoma, Proliferating Infantile Hemangioma, Supraventricular Arrhythmias, Tachyarrhythmia caused by Digitalis intoxication, Tachyarrhythmia caused by catecholamine excess, Thyroid Crisis, Thyrotoxicosis, Tremor caused by lithium, Ventricular Tachycardia (VT)
- Associated Therapies
- -
Propranolol Adjuvant Treatment of Focal Refractory Epilepsy (PATFRE)
- First Posted Date
- 2024-12-06
- Last Posted Date
- 2024-12-10
- Lead Sponsor
- Xuanwu Hospital, Beijing
- Target Recruit Count
- 15
- Registration Number
- NCT06719804
Propranolol Plus Standard Radiation Therapy Before Surgery for the Treatment of Patients With Soft Tissue Sarcoma
- First Posted Date
- 2024-11-01
- Last Posted Date
- 2024-11-01
- Lead Sponsor
- Roswell Park Cancer Institute
- Target Recruit Count
- 12
- Registration Number
- NCT06670976
- Locations
- 🇺🇸
Roswell Park Cancer Institute, Buffalo, New York, United States
Aging, Beta Blockers, and Thermoregulatory Responses
- Conditions
- Interventions
- First Posted Date
- 2024-09-03
- Last Posted Date
- 2024-10-21
- Lead Sponsor
- University of Texas Southwestern Medical Center
- Target Recruit Count
- 22
- Registration Number
- NCT06582680
- Locations
- 🇺🇸
IEEM Texas Health Presbyterian Hospital Dallas, Dallas, Texas, United States
Comparison of the Effectiveness of First-line Preventive Treatment of Migraine in Primary Care
- Conditions
- Interventions
- First Posted Date
- 2024-07-12
- Last Posted Date
- 2024-07-12
- Target Recruit Count
- 460
- Registration Number
- NCT06499116
Valproate Versus Propranolol in Migraine
- Conditions
- Interventions
- First Posted Date
- 2024-07-03
- Last Posted Date
- 2024-07-03
- Lead Sponsor
- Kafrelsheikh University
- Target Recruit Count
- 600
- Registration Number
- NCT06485726
- Locations
- 🇪🇬
Kafr Elsheikh University Hospital, Kafr Ash Shaykh, Egypt
Impact of Early Aging and Menopause on the Vascular Responses to Hypoxia
- Conditions
- Interventions
- First Posted Date
- 2024-05-16
- Last Posted Date
- 2024-10-01
- Lead Sponsor
- University of Missouri-Columbia
- Target Recruit Count
- 75
- Registration Number
- NCT06417177
- Locations
- 🇺🇸
University of Missouri-Columbia, Columbia, Missouri, United States
Zonisamide Versus Propranolol in Migraine
- First Posted Date
- 2024-04-11
- Last Posted Date
- 2024-04-23
- Lead Sponsor
- Kafrelsheikh University
- Target Recruit Count
- 600
- Registration Number
- NCT06361446
- Locations
- 🇪🇬
Kafr Elsheikh University Hospital, Kafr Ash Shaykh, Egypt
Beta-Blocker Influences on Inflammatory and Neural Responses to Stress
- First Posted Date
- 2024-02-16
- Last Posted Date
- 2024-05-09
- Lead Sponsor
- University of North Carolina, Chapel Hill
- Target Recruit Count
- 120
- Registration Number
- NCT06263452
- Locations
- 🇺🇸
Social Neuroscience and Health Laboratory, Chapel Hill, North Carolina, United States
Propranolol for the Treatment of Traumatic Brain Injury
- Conditions
- Interventions
- First Posted Date
- 2024-02-15
- Last Posted Date
- 2024-02-15
- Lead Sponsor
- London Health Sciences Centre
- Target Recruit Count
- 50
- Registration Number
- NCT06262061
Examining Safety, Efficacy and Feasibility of Preoperative Propranolol in Patients With PDAC.
- First Posted Date
- 2023-11-22
- Last Posted Date
- 2024-03-28
- Lead Sponsor
- Zealand University Hospital
- Target Recruit Count
- 30
- Registration Number
- NCT06145074
- Locations
- 🇩🇰
Department of Surgical Gastroenterology, København, Denmark
🇩🇰Ismail Gögenur, Køge, Denmark
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.