Multidetector Raw CT as a Single Tool in the Setting of Ischemic Stroke

Not Applicable

Completed

• Conditions: Ischemic Stroke
• Interventions: Device: Multidetector raw CT

• Registration Number: NCT00708188
• Lead Sponsor: Hospices Civils de Lyon

Brief Summary

This is a prospective study including acute ischemic stroke patients aged 18 to 90. Multidetector raw CT is performed in acute ischemic stroke patients. Heart, neck vessels and brain arteries are studied during the same acquisition. Results are compared with the standard methods including transesophageal echocardiography (TEE), Doppler ultrasound (DUS) and MR angiography (MRA) of neck vessels. The main criteria is the ability of CT to classify the stroke etiology correctly according to the TOAST classification in comparison with the standard methods.

Detailed Description

Not available

Study Timeline

• Study Start: 2008-03
• Study First Submitted: 2008-06-30
• Study First Submitted QC: 2008-06-30
• Study First Posted: 2008-07-02
• Primary Completion: 2013-04
• Study Completion: 2013-04
• Status Verified: 2013-07
• Last Update Submitted: 2019-05-23
• Last Update Posted: 2019-05-28

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 49

Inclusion Criteria

• Acute (< 1 week) ischemic stroke patient aged 18 to 90
• Informed consent obtained
• Presence of health insurance

Exclusion Criteria

• Pregnancy or absence of efficient contraceptive method
• Allergy
• Allergy to contrast material
• Asthma
• Renal failure (blood creatinine > 130 µmoles/l, creatinine clearance < 80 ml/mn according to Cockroft method)
• Myeloma
• Hyperthyroidism (uncontrolled)
• Difficulties to synchronize CT to heart rhythm
• Contra-indication to TEE or MRI
• Absence or retirement of informed consent
• Absence of health insurance

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
Multidetector raw CT	Multidetector raw CT	-

Primary Outcome Measures

Name	Time	Method
Ability of CT to classify the stroke etiology correctly (TOAST classification) in comparison to reference methods (MRA, DUS, TEE)	classify the stroke etiology

Secondary Outcome Measures

Name	Time	Method
Ability of CT to detect the source of stroke in each etiological group. Reliability of CT in quantitative measures of artery stenosis, aortic atheroma, heart thrombus, heart tumors). Tolerance of CT	detect the source of stroke

Trial Locations

Locations (1)

Hôpital Cardiologique Louis Pradel; 🇫🇷 Bron, France