Chemoradiotherapy versus Radiotherapy alone in post-operative locally advanced oral cavity cancer
Phase 3
- Conditions
- Health Condition 1: C00-C14- Malignant neoplasms of lip, oral cavity and pharynx
- Registration Number
- CTRI/2024/06/069157
- Lead Sponsor
- Department Of Radiotherapy and Radiation medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Histologically proven postoperative oral cavity carcinoma, squamous-cell carcinoma histology, three or more minor risk factors (include T4/T3 disease, multiple lymphnodes, a surgical margin =5 mm, moderate and poor differentiation, perineural invasion, vessel invasion, lymphovascular invasion, and tumor invasion depth = 10mm, age of 18 to 70 years of either sex, ECOG of 0 -1, adequate hematologic, renal, and hepatic function, adequate Creatinine clearance
Exclusion Criteria
Presence of positive resection margins, extra capsular spreading in metastatic nodes, history of previous cancer, second synchronous malignancy, any contraindication for concurrent chemotherapy and radiotherapy.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method