A COMPARATIVE DOUBLE BLIND STUDY - PREOPERATIVE NEBULIZATION WITH KETAMINE AND DEXMEDETOMIDINE ON THE INCIDENCEOF POSTOPERATIVE SORE THROAT
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 302
- 试验地点
- 1
- 主要终点
- A comparative double blind study, preoperative nebulisation with kketamine and dexmeditomidine on the incidence of post operative sore throat.
研究概览
简要总结
Ethical approval will be obtained from ethical committee, once patient enter the pre operative room,the patient will be informed about the the study in a language they fully comprehend , they will be enrolled in study after taking written informed consent , the enrolled study participant will be randomisedinto 2 groups by chit method, A double blind technique will be used, the principal investigator and the patient will be blind about the nebulization and unaware of group allocation, Generl anaesthesia will be administred 15mins after nebulisation, post operative sore throat will monitored at 0,4,6,12,24 hrs.
研究设计
- 研究类型
- Interventional
- 分配方式
- Other
- 盲法
- Participant and Investigator Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •Age group 18-60 yrs, Either sex, American society of anaesthesiologist ASA I & II, Surgery in supine position under GA lasting for more than 2hrs.
排除标准
- •history of prior sore throat, patient with chronic usage of steroids or NSAIDS, pregnant women, patient requiring more than 2 attempts of intubation, patient on beta blocker, patient having asthma, hypertension etc.
结局指标
主要结局
A comparative double blind study, preoperative nebulisation with kketamine and dexmeditomidine on the incidence of post operative sore throat.
时间窗: Post operative sore throat will be assesed at 0 hr, 4hr, 6hr, 12 hr, 24hr.
次要结局
- A comparative double blind study, preoperative nebulisation with kketamine and dexmeditomidine on the incidence of post operative sore throat.(post operative sore throat will be assessed at 0 hr, 4hr,6 hr, 8hr, 12hr, 24 hr over a period of 2 years)