A COMPARATIVE RANDOMISED DOUBLE BLIND STUDY - PREOPERATIVE NEBULIZATION WITH KETAMINE AND DEXMEDETOMIDINE ON THE INCIDENCE OF POSTOPERATIVE SORE THROAT

Not yet recruiting

• Conditions: healthy; Medical and Surgical,

• Registration Number: CTRI/2023/06/054022
• Lead Sponsor: Bharati Hospital, pune

Brief Summary

Ethical approval will be obtained from ethical committee, once patient enter the pre operative room,the patient will be informed about the the study in a language they fully comprehend , they will be enrolled in study after taking written informed consent , the enrolled study participant will be randomisedinto 2 groups by chit method, A double blind technique will be used, the principal investigator and the patient will be blind about the nebulization and unaware of group allocation, Generl anaesthesia will be administred 15mins after nebulisation, post operative sore throat will monitored at 0,4,6,12,24 hrs.

Detailed Description

Not available

Study Timeline

• Study Start: 2023-01-07
• Last Update Posted: 2023-02-06

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 302

Inclusion Criteria

Age group 18-60 yrs, Either sex, American society of anaesthesiologist ASA I & II, Surgery in supine position under GA lasting for more than 2hrs.

Exclusion Criteria

history of prior sore throat, patient with chronic usage of steroids or NSAIDS, pregnant women, patient requiring more than 2 attempts of intubation, patient on beta blocker, patient having asthma, hypertension etc.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
A comparative double blind study, preoperative nebulisation with kketamine and dexmeditomidine on the incidence of post operative sore throat.	Post operative sore throat will be assesed at 0 hr, 4hr, 6hr, 12 hr, 24hr.

Secondary Outcome Measures

Name	Time	Method
A comparative double blind study, preoperative nebulisation with kketamine and dexmeditomidine on the incidence of post operative sore throat.	post operative sore throat will be assessed at 0 hr, 4hr,6 hr, 8hr, 12hr, 24 hr over a period of 2 years

Trial Locations

Locations (1)

Bharati hospital and research centre, dhankawadi, pune; 🇮🇳 Pune, MAHARASHTRA, India

Bharati hospital and research centre, dhankawadi, pune

🇮🇳Pune, MAHARASHTRA, India

Dr Sarita swami

Principal investigator

9822846369

drswamisarita@yahoo.in