Optimization of Preventive Effects of Physical Training

Not Applicable

Completed

• Conditions: Primary Prevention, Cardiovascular Risk Factor Management, Size of Response to Training
• Interventions: Other: different training programs; Other: control condition

• Registration Number: NCT01263522
• Lead Sponsor: Universität des Saarlandes

Brief Summary

Health-promoting effects of physical exercise are well-investigated especially for endurance activities. However, for different individuals, positive effects have different sizes, even non-responders are observed. Other forms of training, such as strength training and interval training, are less well investigated. Therefore, a comparative longitudinal training study is warranted to examine differences of preventive effects (outcome measures: ergometric descriptors of physical performance, established risk factors and prognostic factors for cardiovascular diseases) of continuous endurance training, interval training and strength endurance training.

In a second stage, the observed non-responders will perform a different type of training (cross-over). It is expected, that besides a comparative general efficacy evaluation of the three training types, improved recommendations for optimized individualization of training parameters can be formulated.

Detailed Description

Not available

Study Timeline

• Study Start: 2010-12
• Study First Submitted: 2010-12-17
• Study First Submitted QC: 2010-12-17
• Study First Posted: 2010-12-20
• Primary Completion: 2013-12
• Study Completion: 2013-12
• Status Verified: 2018-05
• Last Update Submitted: 2018-05-04
• Last Update Posted: 2018-05-11

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 266

Inclusion Criteria

• untrained
• healthy
• non-smoking

Exclusion Criteria

• Contraindications for physical activity
• BMI > 30 kg/m2
• resting blood pressure > 160/100 mmHg
• diabetes
• total cholesterol > 300 mg/dl
• maximal oxygen uptake > 50 ml/min/kg for men and > 45 ml/min/kg for women respectively
• other complaints or diseases that might interfere with exercise training

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
strength endurance training	different training programs	-
Endurance training	different training programs	-
interval training	different training programs	-
control	control condition	-

Primary Outcome Measures

Name	Time	Method
VO2 max	6 months	determined during treadmill testing

Secondary Outcome Measures

Name	Time	Method
resting heart rate	6 months
resting blood pressure	6 months
blood lipid profile	6 months	ratio: total cholesterol/HDL-cholesterol

Trial Locations

Locations (1)

Institute of Sports and Preventive Medicine, Saarland University, Bldg. B 8-2, 66123 Saarbrücken; 🇩🇪 Saarbrücken, Saarland, Germany