The Acute Effects of Brain Activation and Functional Connectivity Following Motor-cognitive Training Using Functional MRI
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 21
- 试验地点
- 2
- 主要终点
- Change in brain activation
研究概览
简要总结
Participants will complete a functional MRI to evaluate brain activation, functional connectivity, and behavioral performance immediately before and after a training program (approximately 30 minutes). The training program will comprise of integrate neuromuscular (agility, dynamic postural stability, shuffling, rapid acceleration/deceleration, plyometrics, lateral shuffle, and core stability) and cognitive (reaction time, processing speed, task switching, decision-making, and working memory) challenges.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Prevention
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 25 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •Physically active
排除标准
- •Injury to the muscle or bone (upper extremity, lower extremity, or back) within the past 3 months
- •Had musculoskeletal surgery or fracture (required open reduction internal fixation or within the last 12 months)
- •Had a concussion or mild head injury within the last year
- •Have been diagnosed with any kind of neurological, vestibular, or visual disturbance that impairs mobility
- •Currently taking medications that affect the central nervous system
- •Pregnant or suspicions of being pregnant
- •Have metal fragments, pins, plates, or clips, shrapnel, body piercings that cannot be removed, have surgical implants or orthodontics that cannot be removed
- •Have claustrophobia
- •Have a history of cognitive impairment
结局指标
主要结局
Change in brain activation
时间窗: 2 hours, pre-training session and immediately post-training session
During the task-based functional MRI scan the participant will complete a task-switching cognitive task, where participants have to identify two possible shapes (circle or square), in one of two possible colors (red or blue). They will respond using a trigger under their left and right foot. The level of brain activation during the task will be captured and reported.
Change in functional connectivity
时间窗: 2 hours, pre-training session and immediately post-training session
The participant will complete a resting-state functional MRI scan in which they will lay still in the scanner. No task is performed during this scan. Functional connectivity (functionally related regions of the brain that are co-activated) during the scan will be captured and reported.
Change in reaction time
时间窗: 2 hours, pre-training session and immediately post-training session
During the task-based functional MRI scan the participant will complete a task-switching cognitive task, where participants have to identify two possible shapes (circle or square), in one of two possible colors (red or blue). They will respond using a trigger under their left and right foot. The reaction time in milliseconds will be captured. The change in reaction time from pre to post training session will be reported.
Change in accuracy
时间窗: 2 hours, pre-training session and immediately post-training session
During the task-based functional MRI scan the participant will complete a task-switching cognitive task, where participants have to identify two possible shapes (circle or square), in one of two possible colors (red or blue). They will respond using a trigger under their left and right foot. The percent of correct responses (accuracy) will be captured. The change in accuracy from pre to post training session will be reported.
次要结局
- Modified Disablement In Physically Active Scale(Once, pre-training)
- NASA Physical Activity Survey(Once, pre-training)
- Defense Veterans Pain Rating Scale(Once, pre-training)
- Heart rate(35 minutes, during the training session)
- Average reaction time during the intervention(30 minutes, during the training session)
- Misses during the training session(30 minutes, during the training session)
- Perceived cognitive difficulty(30 minutes, during the training session)
- Demographic/Injury History Form(Once, pre-training)
- Number of errors during the training session(30 minutes, during the training session)
- Hits during the training session(30 minutes, during the training session)
- Rate of perceived exertion(30 minutes, during the training session)
研究者
Ke'La H Porter
Research Analyst Principal
University of Kentucky