FMRI Assessment After Radiofrequency in Trigeminal Neuralgia
Not Applicable
- Conditions
- Pain, NeuropathicTrigeminal Neuralgia
- Registration Number
- NCT03305289
- Lead Sponsor
- Assiut University
- Brief Summary
To investigate the brain activations related to TN, using fMRI, and to evaluate changes in these activations following the application of pulsed and thermal Radiofrequency lesioning to the gasserien ganglion.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 20
Inclusion Criteria
- Age 20 - 65 years
- Primary trigeminal neuralgia
- Maxillary and/or mandibular affection only
- Failure of medical treatment
Exclusion Criteria
- 2ry trigeminal neuralgia
- Recurrent trigeminal neuralgia
- Ophthalmic branch affection
- Contraindication for intervention (sepsis, coagulopathy, infection at entery point, local anesthetic allergy,...)
- Pregnancy
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method pain alleviation 1 month pain assessment by functional MRI
- Secondary Outcome Measures
Name Time Method
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms underlie trigeminal neuralgia pain modulation via pulsed radiofrequency lesioning of the gasserian ganglion?
How does thermal radiofrequency compare to pulsed radiofrequency in modulating brain activity for trigeminal neuralgia patients?
Are there specific biomarkers that predict response to gasserian ganglion radiofrequency lesioning in trigeminal neuralgia?
What are the long-term adverse events associated with pulsed and thermal radiofrequency treatments for neuropathic pain?
How does radiofrequency lesioning of the gasserian ganglion compare to microvascular decompression in trigeminal neuralgia management?