?Effects of Metronidazole gel and tablets in gingival disease treatment

Phase 3

Recruiting

• Conditions: Chronic Periodontitis.; Chronic periodontitis; K05.3

• Registration Number: IRCT20210408050898N1
• Lead Sponsor: Oroumia University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 26 May 2021

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

Patient diagnosed with chronic periodontitis with at least three non-adjacent pockets with probing depth equal to or greater than 4 mm.
Patients with systemic health.
Patients who have not taken any anti-inflammatory drugs or antibiotics in the last six months.
Patients with at least 15 teeth (except third molars) in their mouth.
Patients with proper cooperation.
Patients who have signed an informed written consent form.

Exclusion Criteria

Patients with medical problems who need antibiotic prophylaxis or treatment intervention.
Patients who have had periodontal treatment in the last six months.
Patients who have used drugs that affect their periodontal status (such as antibiotics, anti-inflammatory drugs, anticonvulsants, immunosuppressive drugs, and calcium channel blockers) in the last six months.
Patients who have undergone orthodontic treatment.
Pregnant and lactating patients.
Patients with systemic diseases such as diabetes and immunological disorders.
O’Leary plaque index more than 15% after proper oral hygiene training.
History of Metronidazole allergy.

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Pocket Probing Depth. Timepoint: At the beginning of the study (before the intervention) and three months after the intervention. Method of measurement: Periodontal Probe.;Clinical Attachment Level. Timepoint: At the beginning of the study (before the intervention) and three months after the intervention. Method of measurement: Periodontal Probe.;Bleeding On Probing. Timepoint: At the beginning of the study (before the intervention) and three months after the intervention. Method of measurement: Visual.