Effect of Topical Metronidazole in treatment of chronic fissure

Phase 3

Recruiting

• Conditions: Chronic Anal Fissure.; Chronic anal fissure; K60.1

• Registration Number: IRCT20221102056377N1
• Lead Sponsor: Shahid Beheshti University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 7 February 2023

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 54

Inclusion Criteria

All individuals with anal fissures for more than 6 weeks

Exclusion Criteria

Suffering from other colorectal diseases
The person is unable to participate in follow-up visits
Duration of symptoms less than 6 weeks

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Determination of pain intensity in patients with chronic anal fissure treated with Metronidazole gel and diltiazem. Timepoint: Determination of pain intensity in patients with chronic anal fissure at the beginning of the study and 10, 21, 28 days after starting Metronidazole. Method of measurement: Examination of Anus; Use of Visual Analogue Scale.;Determining the duration of pain in patients with chronic anal fissure treated with Metronidazole gel and Diltiazem. Timepoint: Determining the duration of pain in patients with chronic anal fissure at the beginning of the study and 10, 21, 28 days after starting Metronidazole. Method of measurement: Questionnaire.