The effect of vaginal cream Prangos ferulacea Brghvnt Trichomonas vaginalis

Phase 3

Conditions: Trichomoniasis vaginit.
Trichomonal vulvovaginitis
A59.01

Registration Number: IRCT20160423027534N2

Lead Sponsor: Shahid Beheshti University of Medical Sciences

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Complete

Sex: Female

Target Recruitment: 90

Inclusion Criteria

15-49 year old married women
Non pregnant
Non breast feeding
Non menopause
Non smoker
Willing to participate in the research
Complaine with foamy yellow green discharge
Not having vaginal infections
Not having unusual vaginal bleeding during the treatment
Not intercoursing during the treatment
Not using vaginal ointment,suppository or douching from two days before treatment
Not having chronic diseases like heart or kidney problems, diabetes, arthoritis
Not using broad-spectrum antibiotics, hormones, anticoagulant and immunosuppressive medicine
Not having allergic to metronidazole or topical medications

Exclusion Criteria

Unwilling to continue to participate in the reseach
Not using vaginal ointment for two consecutive days
Being allergic to metronidazole or Prangos ferulacea vaginal cream or intolerance to any forms of medicine
Having vaginal infections (bacterial vaginosis and candidiasis)
having intercourse during in the treatment
become pregnant during treatment
incomplete questionnaire

Study & Design

Study Type: interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
1- Evaluation of vaginal secretions in terms of color, odor by direct observation.2. Transient trichomoniasis (under microscope) in wet smear. Timepoint: Before interference and 7 days after treatment. Method of measurement: At first, the secretions and symptoms will be examined with direct vision. Then, using sterile cotton swabs, a vaginal discharge was taken and a 10% potassium solution was prepared on a lavender discharge prepared with sterile cotton swabs. And immediately poured a drop of saline samples under a microscope with a magnification of 400 (× 40) was seen moving trophozoite information.;Observe the wet slides with a microscope. Timepoint: Before interference and 7 days after treatment. Method of measurement: With sterile cotton swabs, a sample of the secretions of the side walls of the vagina was removed and immediately underneath the microscope with magnification (× 40). If trichomoniasis is present in wet pearl trophozoites, they are approved.

Secondary Outcome Measures

Name	Time	Method
Trichomoniasis vaginitis. Timepoint: En Before the intervention, seven days after start treatment. Method of measurement: Samples are discharge from the sample by using the pH meter Strip, and after wetting the pH Strip, the color will change, and if the pH of the vaginal discharge is between 6-5, a wet test is performed.