Physical exercise prior to hematopoietic stem cell transplantatio

Completed

Conditions: Patients diagnosed with acute or chronic leukemia, Hodgkin?s Lymphoma, non-Hodgkins?s Lymphoma or Multiple Myeloma, and scheduled to undergo an allogenic or autologous HSCT
Cancer

Registration Number: ISRCTN30955874

Lead Sponsor: Scientific Institute for Quality of Healthcare (Netherlands)

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Completed

Sex: All

Target Recruitment: 30

Inclusion Criteria

In order to be selected they need to meet the following inclusion criteria:
1. Diagnosed with acute or chronic leukemia, Hodgkin?s Lymphoma, non-Hodgkins?s Lymphoma or Multiple Myeloma
2. Scheduled to undergo an allogenic or autologous HSCT
3. Sufficient knowledge of the Dutch language
4. Approval to participate in the study by the treating physician, and
5. Being aged in the age range 18 years through 65 years, either sex

Exclusion Criteria

1. Cardiovascular or other contra-indications (e.g. rheumatic disease) for participating in a physical exercise program. Decisions to exclude potential participants will be made based on the results of the Physical Activity Readiness Questionnaire (PAR-Q) and after consultation with the physician.

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
1. For the primary outcomes self-perceived physical functioning and QOL, patients fill out the Short Form Health Survey (SF-36). With the SF-36, 36 questions are answered to score perceived health related to quality of life (QOL). With this questionnaire 36 questions are grouped into eight domains of which our primary outcome ?self-perceived physical functioning? is one domain. All scores in the SF-36 range from 0-100 points (higher scores are related to better outcome). For QOL, a physical component score (PCS) and a mental component score (MCS) can be derived from the total SF-36 score.<br>2. With the Checklist Individual Strength (CIS) the primary score for severity in fatigue was evaluated. The questionnaire consists of four domains, of which ?Severity of Fatigue? is one domain. The total CIS score (ranging from 20-140 points) and the score of ?Severity of Fatigue? (ranging from 8-56 points) are evaluated in this study.

Secondary Outcome Measures