Effectiveness of Oral Midazolam for Sedation in Patients Undergoing Upper Gastrointestinal Endoscopy
Overview
- Phase
- Phase 4
- Intervention
- Oral midazolam
- Conditions
- Conscious Sedation Failure During Procedure
- Sponsor
- Phramongkutklao College of Medicine and Hospital
- Enrollment
- 260
- Locations
- 1
- Primary Endpoint
- Difference of Anxiety score
- Last Updated
- 11 years ago
Overview
Brief Summary
Can oral midazolam used for sedation in patients undergoing upper gastrointestinal endoscopy ?
Detailed Description
Five mg of midazolam was intake orally about 30 minutes before undergoing perform upper gastrointestinal endoscopy. Declined of anxiety scores was primary end point.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Scheduled to undergo elective diagnostic EGD
- •American Society of Anesthesia (ASA) criteria to be class 1 to 2
Exclusion Criteria
- •History of gastrectomy, esophagectomy, pancreaticoduodenectomy, or other operation on the upper-GI tract
- •American Society of Anesthesia (ASA) criteria to be class 3 to 4
- •Pregnancy
- •Alcoholism
- •Drug abuse
- •Taking psychotic medications
- •Allergy to midazolam.
Arms & Interventions
Oral midazolam
Oral midazolam (5 mg) in 15 mL of apple juice was drunk 30 minutes before EGD
Intervention: Oral midazolam
Outcomes
Primary Outcomes
Difference of Anxiety score
Time Frame: Asked the patient 5 minutes before EGD and then after fully recovery from sedation.
* Anxiety score is 10-cm scaled visual analog scale. * Anxiety score which asked the patient 5 minutes before EGD, called "Pre EGD anxiety score" * Anxiety score which asked the patient after fully recovery, called "During EGD anxiety score". * Difference of anxiety score means "Pre EGD minus During anxiety score". * Fully recovery means fully gain of consiouness (time, place, person).
Secondary Outcomes
- Overall tolerance(Asked the patient after fully recovery from sedation.)