Magnetic Prefrontal Stimulation for Studying the Role of the Cortex in High-level Cognition Processes and Reward System

Early Phase 1

Completed

• Conditions: Healthy Volunteers
• Interventions: Device: TMS

• Registration Number: NCT00912522
• Lead Sponsor: Hadassah Medical Organization

Brief Summary

The investigators intend to study the role of the cortex in high- level cognition processes and sensory adaptation, by the use of non-invasive Transcranial Magnetic stimulation and various cognitive tests.

Detailed Description

Not available

Study Timeline

• Study Start: 2009-06
• Study First Submitted: 2009-06-02
• Study First Submitted QC: 2009-06-02
• Study First Posted: 2009-06-03
• Primary Completion: 2014-06
• Study Completion: 2014-06
• Status Verified: 2015-04
• Last Update Submitted: 2015-04-20
• Last Update Posted: 2015-04-22

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 91

Inclusion Criteria

• healthy men and women, age of 18-60
• answered negatively to questions of TMS safety questionnaire
• signed and declared about their agreement to participate in the study
• hebrew speaker

Exclusion Criteria

• self history of significant mental disorder
• self history or first-degree relatives history of epilepsy

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
LT PFC HIGH FREQ TMS	TMS	-
LT PFC LOW FREQ TMS	TMS	-
RT PFC LOW FREQ TMS	TMS	-
SHAM STIMULATION	TMS	-
RT PFC HIGH FREQ TMS	TMS	-

Primary Outcome Measures

Name	Time	Method
Changes in scoring of different tests and questionnaires	One year

Secondary Outcome Measures

Name	Time	Method
Correlation of different tests and questionnaires	One year

Trial Locations

Locations (1)

Hadassah medical org; 🇮🇱 Jerusalem, Israel