COMPARISON OF BLOOD FLOW IN BRAIN WITH BLOOD THICKNESS IN NEONATES AT RISK OF HAVING BLOOD THICKENING
Not Applicable
Completed
- Registration Number
- CTRI/2022/09/045696
- Lead Sponsor
- RAINBOW CHILDRENS HOSPITA
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 75
Inclusion Criteria
neonates with gestational age more than 35 weeks and having one or more risk factors for polycythemia which includes SGA, LGA, IDM, Post maturity, gestational hypertension, large twin of monochorionic twin
Exclusion Criteria
sick neonates requiring NICU admission, in whom consent is denied
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method to correlate PSV of ACA, MCA with hematocrit with neonate at risk of polycthemiaTimepoint: PSV measured between 2 and 6 hour of life and one more time before discharge / after 36 hours of life <br/ ><br>1st Haematocrit measured between 2 and 6 hour of life, subsequent Haematocrit measured after 36 hours/before discharge if Initial measured Haemotocrit is more than 65%
- Secondary Outcome Measures
Name Time Method to compare cerebral blood flow velocity, RI in neonates with polcythemia and normocythemiaTimepoint: Cerebral blood flow velocity RI measured initially between 2 and 6 hour of life and subsequently after 36 hours of life/ before discharge
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms link cerebral blood flow velocity to hematocrit in neonatal polycythemia?
How does increased blood viscosity from polycythemia affect neonatal cerebral hemodynamics and oxygen delivery?
Are there specific biomarkers that correlate with abnormal cerebral blood flow in high-risk neonates for polycythemia?
What adverse events are associated with untreated neonatal polycythemia and how do they relate to cerebral blood flow changes?
How do current observational strategies for cerebral blood flow in neonates compare to interventional approaches in managing polycythemia?