跳至主要内容
临床试验/NCT06437561
NCT06437561已完成不适用

Venous Aneurysm: a Case Series and Review of Literature

Golestan University of Medical sciences1 个研究点 分布在 1 个国家目标入组 10 人开始时间: 2024年2月13日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
10
试验地点
1
主要终点
age distribution of extremity venous aneurysms

研究概览

简要总结

Venous aneurysms are not common in general, but because of the inherent risk of thrombosis in aneurysms, their timely diagnosis and treatment are recommended in most of the current sources. Ten cases of venous aneurysms were diagnosed and managed in our vascular surgery department from October 2018 to January 2024. Patient information was extracted from their files retrospectively.

详细描述

A vascular aneurysm is defined as the focal dilatation of a vessel. Aneurysm is classically used for arterial dilatations, although dilatations can occur in any part of the vascular system including veins. Venous aneurysms are not common in general, but with the increase in the use of duplex ultrasound, the number of cases diagnosed with venous aneurysms has recently increased. Venous aneurysms are more common in the lower limbs, and in the lower limbs, the involvement of the deep venous system is much more than the superficial venous system. According to reports, 77% of venous aneurysms are present in the lower limbs, of which 57% are in the deep venous system and 1.5% in the superficial venous system.

Considering their rarity, venous aneurysms may cause diagnostic challenges in some cases.

The importance of these aneurysms, especially in the lower limbs, which inherently have relative stasis due to the opposite flow direction of gravity, is that by creating venous stasis and whirlwind blood flow inside the aneurysm, they increase the susceptibility to clotting. Also, due to dysfunction of the pigeon nest valves, they cause chronic venous insufficiency. Although clot formation and subsequent pulmonary embolism are more common in deep venous aneurysms, cases of pulmonary embolism secondary to superficial venous aneurysms of the lower limbs have also been reported.

Complications caused by chronic venous insufficiency are more common in aneurysms that occur at the main junctions of superficial and deep veins, including saphenous femoral and saphenous popliteal junctions.

Considering the possible complications mentioned about venous aneurysms, these aneurysms need treatment, regardless of their location, and although in the superficial system, surgical resection is the most commonly recommended method, other surgical methods such as aneurysmectomy and primary repair, resection, and graft interposition, and also endovascular methods have been used. Of course, in case of insufficiency in the venous system, specific treatment of the cause of insufficiency (such as stripping of the large saphenous vein) is necessary in addition to the treatment of the aneurysm.

研究设计

研究类型
Observational
观察模型
Case Only
时间视角
Retrospective

入排标准

性别
All
接受健康志愿者

入选标准

  • Clinical diagnosis of venous aneurysm

排除标准

  • Patient's non-consent

结局指标

主要结局

age distribution of extremity venous aneurysms

时间窗: 6 years

prevalence of extremity venous aneurysms in different ages

location distribution of extremity venous aneurysms

时间窗: 6 years

prevalence of extremity venous aneurysms in upper vs. lower limbs as well as left side vs. right side

sex distribution of extremity venous aneurysms

时间窗: 6 years

prevalence of extremity venous aneurysms in both sexes

clinical presentation of extremity venous aneurysms

时间窗: 6 years

different clinical presentations of extremity venous aneurysms and their prevalence

次要结局

未报告次要终点

研究者

发起方
Golestan University of Medical sciences
申办方类型
Other
责任方
Principal Investigator
主要研究者

Pezhman Kharazm, MD

Vascular Surgeon

Golestan University of Medical sciences

研究点 (1)

Loading locations...

相似试验