To study the causes of irregular menses in young girls.

Not yet recruiting

• Conditions: Polycystic ovarian syndrome, (2) ICD-10 Condition: E282||Polycystic ovarian syndrome,

• Registration Number: CTRI/2020/09/027760
• Lead Sponsor: AIIMS

Brief Summary

Many young girls complain of  irregular mentrual cycles,though the problems often are unreported.The exact cause of irregular menses in adolescent and young girls is not clearly established as in many girls this may be part of development. The objective of this study is to correlate the menstrual irregularities with factors of glucose and fat metabolism  and hormonal parameters. The participants will be in the age group of 14-21 years presenting with menstrual irregularity. .The participants will be evaluated by detailed history taking ,physical examination anthropometric prameters, hirsutism by Ferriman Gallwey score and acne by global acne grading system. Blood samples will be taken for hormonal and metabolic parameters. No intervention will be done.The main outcome will be seen as correlation of menstrual irregularities with BMI and metabolic parameters,hyperandogenemia with serum AMH levels.

Detailed Description

Not available

Study Timeline

• Study Start: 2020-09-15
• Last Update Posted: 2020-10-09

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: Female
• Target Recruitment: 100

Inclusion Criteria

Adolescents and young girls in the age group of 14 -21 years with menstrual irregularities.

Exclusion Criteria

• 1.Pregnancy 2.Any chronic medical or surgical illness.
• 3.Taking or history of taking any hormonal treatment over the past 3 months.
• 4.Taking or history of taking glucocorticoids,lipid lowering drugs,glucose lowering drugs or anti obesity drugs within 3 months of study.

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
1.Clinical-BMI,WHR,Modified FG score.	Day 2 LH,FSH,S.testosterone,AMH at the time of recruitement. | BMI at the time of recruitement.
2.Hormonal-Serum FSH,LH,AMH,Testosterone	Day 2 LH,FSH,S.testosterone,AMH at the time of recruitement. | BMI at the time of recruitement.
To evaluate the clinical and hormonal characteristics of young adolescents girls with menstrual irregularity.	Day 2 LH,FSH,S.testosterone,AMH at the time of recruitement. | BMI at the time of recruitement.

Secondary Outcome Measures

Name	Time	Method
1.To correlate menstrual irregularity with metabolic parameters1(SHBG,Lipid profile,GTT)	2. To correlate s. AMH with BMI in adolescents with menstrual irregularities.

Trial Locations

Locations (1)

All India Institute of Medical Sciences; 🇮🇳 Delhi, DELHI, India

All India Institute of Medical Sciences

🇮🇳Delhi, DELHI, India

Dr Garima Kachhawa

Principal investigator

9868246702

garimakhadgawat@gmail.com