Clinical research a siddha drug in the treatment ofPaithiyavatha Suronitham(Advanced stage of Rheumatoid Arthritis)
Phase 3
- Conditions
- Health Condition 1: null- PAITHIYAVATHASURONITHAM (ADVANCED STAGE OF RHEUMATOID ARTHRITIS)
- Registration Number
- CTRI/2014/09/005046
- Lead Sponsor
- Ayothidoss pandithar hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 40
Inclusion Criteria
1.Onset of arthritis after the age of 16 years.
2.Positive for rheumatoid factor(RF).
3.Anti-CCP.
4.Either an erythrocyte sedimentation rate(ESR) of greater than 30mm/hr(OR)C-reactive protein level greater than 1.0mg/dl.
5.Diagnosis of PaithiyavathaSuronitham, as defined by fulfilling at least more than two articular involvement.
Exclusion Criteria
1.Diabetes mellitus
2.Hypo & Hyperthyroidism
3.Hypertension
4.Cardiac disease
5.Renal disease
6.Liver disorders
7.Neurological disorders
8.Pregnancy and lactation
9.History of alcohol or substance abuse
10.Active infection, or chronic or persistent infection that might worsen with immunosuppressive treatment (e.g., HIV, hepatitis B virus, hepatitis C virus, tuberculosis [TB])
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Pain measured by Visual analogue scaleTimepoint: Before Treatment (0th day) and After Treatment(60th day)
- Secondary Outcome Measures
Name Time Method : Improving the other manifestations such as duration of morning stiffness (in minutes), Onset of fatigue (in minutes) after walking, Ritchies articular index for pain joints at each visit. <br/ ><br>â?¢Hb, CRP, RF, and ESR under normal limits after completion of study <br/ ><br>Timepoint: Before treatment and After treatment