Comparision of two different drugs(ketamine and 3%NS) filled in definite airway tube and its results on extubation response vitals and post operative sorethroat, hoarseness,cough response.

Not yet recruiting

• Conditions: Calculus of kidney with calculus of ureter, (2) ICD-10 Condition: G968||Other specified disorders of central nervous system,

• Registration Number: CTRI/2022/09/046003
• Lead Sponsor: ESIC MEDICAL COLLEGE AND SUPER SPECIALITY HOSPITAL

Brief Summary

Endotracheal intra cuff instillation of 2 drugs ketamine and 3%NS  after intubation  in patients undergoing elective surgery and cuff pressure maintained around 20-25mmHg by using cuff pressure manometer.

Detailed Description

Not available

Study Timeline

• Study Start: 2022-01-10
• Last Update Posted: 2022-09-24

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 70

Inclusion Criteria

ASA 1 and 2 scheduled for elective surgery.

Exclusion Criteria

1)Patient refusal 2)Already patient on steroids 3)Cardiorespiratory compromise 4)Emergency surgeries 5)Anticipated difficult airway 6)Pregnancy 7)active URTI.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To compare the haemodynamic extubation parameters and incidence and severity of post operative sorethroat	Haemodynamic parameters 0min,3mins,5mins,10mins | post operative sore throat assesed in 0min,30mins,1 hour,24 hours.

Secondary Outcome Measures

Name	Time	Method
Drug effect on postoperative hoarseness and cough.	Assesed in 0min, 30mins, 1hour,

Trial Locations

Locations (1)

ESIC MEDICAL COLLEGE AND SUPER SPECIALITY HOSPITAL; 🇮🇳 Hyderabad, TELANGANA, India

ESIC MEDICAL COLLEGE AND SUPER SPECIALITY HOSPITAL

🇮🇳Hyderabad, TELANGANA, India

DR R SRUJAN GOUD

Principal investigator

7780395335

sruj0029@gmail.com