Evaluation of Short-Term Postoperative Outcomes After Liver Resections in a Tertiary Cancer Institute -An observational study
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- To assess the incidence of Clavien-Dindo complications 3-4 following hepatectomies( both major and minor)
研究概览
简要总结
liver resection continues to play a vital role in the curative treatment of both primary and secondary liver cancers. Although there have been significant advances in surgical methods and perioperative care, rates of morbidity and mortality remain considerable, particularly in patients with pre-existing liver dysfunction or those undergoing extensive resections. identifying factors linked to short term (within 30 days) postoperative outcomes is esssential for improving risk assessment, optimizing perioperative care, and guiding patient discussions. this study is designed to determine the clinical, pathological, and surgical predictors of poor short-term outcomes in patients who undergo liver resections at high-volume tertiary cancer centre. The study will be a combination of prospective and retrospective observational cohort designs, and it will be conducted at ACTREC, tata memorial centre. prospective data will be gathered over a 1 year period from the date of ethics approval (25/9/25), while retrospective data will be collected starting from 1/6/24 till 1/6/25. the study will analyse how perioperative factors, including those related to anesthesia and surgery, affect 30-day postoperative outcomes in liver resection cases. the study population will consist of adult patients (aged 18 and above) who are scheduled for elective liver resections (either major or minor) for malignant tumors. upon admission for surgery, patients will undergo fitness assessments, and written informed consent will be obtained. Patient data will be extracted from electronic medical records (EMR) and case files. postoperative complications will be recorded until the time of discharge and monitored during the 30-day follow-up period, while mortality will be tracked for upto 90 days post-surgery.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18.00 Year(s) 至 99.00 Year(s)(—)
- 性别
- All
入选标准
- •Our inclusion criteria includes Adult patients (age 18 years or older) undergoing elective liver resection (major or minor) for malignant lesions.
排除标准
- •Our exclusion criteria includes emergency liver resections and patients not consenting for the surgery.
结局指标
主要结局
To assess the incidence of Clavien-Dindo complications 3-4 following hepatectomies( both major and minor)
时间窗: To assess the incidence of Clavien-Dindo complications 3-4 following hepatectomies( both major and minor)
次要结局
- To assess the association between morbidity predictors and the outcome variables such as duration of mechanical ventilation (MV), length of stay (LOS) in ICU, LOS in hospital, hospital re-admission within 30 days of discharge, 30-day mortality rate, 90-day mortality rate(30 day morbidity and 90 day mortality follow up)
- To assess the effect of Pringles maneuvre on the postoperative outcomes(30 days post operative)
研究者
malini joshi
actrec, tata hospital, khargar
