Comparison of the effect of maintenance of anesthesia with Propofol versus Isoflurane on haemorrhage during spinal surgery

Phase 3

• Conditions: During surgical operation; haemorrhage.

• Registration Number: IRCT2013011911822N2
• Lead Sponsor: Vice chancellor of Research and Technology, Hamadan University of Medical Science

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 22 February 2018

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

1.Spine surgery for laminectomy
2.Spine surgery for fixation of fracture of vertebral column
3.18-65 years old
4.ASA = II
Exclusion criteria:
1.Refuse patient
2.Allergy to propofol
3.Allergy to soya
4.Allergy to egg
5.Allergy to isoflurane
6.History of malignant hyperthermia in patient and his or her family

Exclusion Criteria

Not provided

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Quality of hemorrhage. Timepoint: each 20 min. Method of measurement: Boezzart criteria.;Volume of blood in suction bottle. Timepoint: At end of surgery. Method of measurement: Milliliter.;Hemoglobin. Timepoint: Preoperative and six hours postoperative. Method of measurement: g/dl.;Blood on gauzes. Timepoint: At end of surgery. Method of measurement: Weighting of gauzes (g).;Blood volume in hemovac drain. Timepoint: The day after surgery. Method of measurement: Milliliter.;Hematocrit. Timepoint: Preoperative and six hours postoperative. Method of measurement: percent.

Secondary Outcome Measures

Name	Time	Method
Mean arterial blood pressure. Timepoint: each 5 min. Method of measurement: Automatic noninvasive blood pressure (mmHg).;Heart rate. Timepoint: each 5 min. Method of measurement: Electrocardiogram monitoring (per min.).;Satisfactory of surgeon. Timepoint: At end of surgery. Method of measurement: Questionnaire.