Compare the effect of methimazole and hydroquinone cream in the treatment of melasma
Not Applicable
- Conditions
- Melasma.Chloasma
- Registration Number
- IRCT2016041727445N1
- Lead Sponsor
- Vice chancellor for research, Shahid Beheshti University Skin Research Centerof Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 25
Inclusion Criteria
All the people in the age range of 50-20 years and all topical treatments for at least one month prior to study entry and are cut by a dermatologist examination with Wood's light examination (Wood) disease of epidermal melasma approved exclusion criteria and do not have;All people have informed consent to participate in the scheme.
Exclusion criteria:Pregnancy and lactation;There Type of melasma
3Use of any treatment for melasma in the last month;Use of oral contraceptives and hormone therapy and medication have any phototoxic;Past medical history of any thyroid disorders in patients
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Efficasy of methimazole 5%cream in severity of melasma with change in colore. Timepoint: Every 4 Weeks. Method of measurement: MASI Score.;Efficacy of hydroquinone 4%cream in severity of melasma with change in colore. Timepoint: Every 4 weeks. Method of measurement: MASI score.
- Secondary Outcome Measures
Name Time Method Side effects. Timepoint: Every four weeks. Method of measurement: Ask the patient.